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GM2A Polyclonal Antibody
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Product Details
BS-13452R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human GM2A/SAP3, amino acids 131-193.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cerebroside sulfate activator protein; Ganglioside GM2 activator; GM2 ganglioside activator; GM2 ganglioside activator protein; GM2-activator protein; GM2-AP; SAP-3; shingolipid activator protein 3; Sphingolipid activator protein 3; unnamed protein product
Gene Aliases: GM2-AP; GM2A; GM2AP; SAP-3
UniProt ID: (Human) P17900
Entrez Gene ID: (Human) 2760, (Rat) 282838
ganglioside metabolic process
lipid metabolic process
sphingolipid metabolic process
ganglioside catabolic process
lipid transport
learning or memory
oligosaccharide catabolic process
lipid storage
glycosphingolipid catabolic process
neurological system process
neuromuscular process controlling balance
positive regulation of catalytic activity
positive regulation of hydrolase activity
membrane fusion
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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