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Bioss
KAT4 Polyclonal Antibody
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Product Details
BS-2812R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human TBP Associated Factor 1, amino acids 501-600.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
3-Phosphoglycerate dehydrogenase (PHGDH; EC 1.1.1.95) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cell cycle gene 1 protein; cell cycle, G1 phase defect; complementation of cell cycle block, G1-to-S; p250; TAF(II)250; TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa; TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, neuron specific isoform; TBP-associated factor 250 kDa; transcription factor TFIID p250 polypeptide; Transcription initiation factor TFIID 250 kDa subunit; Transcription initiation factor TFIID subunit 1
Gene Aliases: AU015687; B430306D02Rik; BA2R; Ccg-1; CCG1; CCGS; DYT3; DYT3/TAF1; KAT4; MRXS33; N-TAF1; NSCL2; OF; P250; RGD1562050; TAF(II)250; TAF1; TAF2A; TAFII-250; TAFII250; XDP
UniProt ID: (Human) P21675, (Mouse) Q80UV9
Entrez Gene ID: (Human) 6872, (Mouse) 270627, (Rat) 317256
nucleotide binding
RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II general transcription initiation factor binding
transcription factor activity, core RNA polymerase I binding
p53 binding
DNA binding
histone acetyltransferase activity
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
obsolete general RNA polymerase II transcription factor activity
kinase activity
transferase activity
transferase activity, transferring acyl groups
ligand-dependent nuclear receptor binding
TBP-class protein binding
sequence-specific DNA binding
protein heterodimerization activity
H3K27me3 modified histone binding
RNA polymerase II sequence-specific DNA binding transcription factor binding
ubiquitin conjugating enzyme activity
peptide-lysine-N-acetyltransferase activity
protein serine kinase activity
histone H4K16ac reader activity
transcription regulator inhibitor activity
histone reader activity
acetyl-CoA binding
transcription coactivator activity
transcription factor binding
lysine-acetylated histone binding
molecular_function
general transcription factor
negative regulation of transcription from RNA polymerase II promoter
protein polyubiquitination
chromatin organization
chromatin remodeling
DNA-templated transcription, initiation
transcription initiation from RNA polymerase I promoter
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
ubiquitin-dependent protein catabolic process
cellular response to DNA damage stimulus
negative regulation of gene expression
midbrain development
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
cellular response to UV
mRNA transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase II promoter
protein autophosphorylation
protein stabilization
RNA polymerase II transcriptional preinitiation complex assembly
positive regulation of transcription initiation from RNA polymerase II promoter
cellular response to ATP
positive regulation of androgen receptor signaling pathway
regulation of signal transduction by p53 class mediator
negative regulation of signal transduction by p53 class mediator
regulation of cell cycle G1/S phase transition
negative regulation of protein autoubiquitination
negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
transcription, DNA-templated
regulation of transcription, DNA-templated
cell cycle
phosphorylation
histone acetylation
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
response to drug
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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