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BMP9 Polyclonal Antibody
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FIGURE: 1 / 3
BMP9 Antibody (BS-6909R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded rat liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with BMP9 Polyclonal Antibody, Unconjugated (bs-6909R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) instructi... View More
Product Details
BS-6909R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human BMP9, amino acids 351-429.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in rodents suggest that this protein plays a role in the adult liver and in differentiation of cholinergic central nervous system neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BMP; BMP-9; Bone morphogenetic protein; Bone morphogenetic protein 9; GDF-2; Growth/differentiation factor 2; secreted protein; GDF-2; transforming growth factor-beta superfamily member; unnamed protein product
Gene Aliases: BMP-9; BMP9; GDF2; HHT5
UniProt ID: (Human) Q9UK05, (Mouse) Q9WV56
Entrez Gene ID: (Human) 2658, (Mouse) 12165, (Rat) 290921
ossification
angiogenesis
patterning of blood vessels
vasculogenesis
osteoblast differentiation
negative regulation of endothelial cell proliferation
positive regulation of endothelial cell proliferation
transcription from RNA polymerase II promoter
cellular iron ion homeostasis
negative regulation of DNA replication
negative regulation of endothelial cell migration
positive regulation of gene expression
negative regulation of angiogenesis
negative regulation of cell growth
BMP signaling pathway
positive regulation of BMP signaling pathway
positive regulation of epithelial cell differentiation
positive regulation of interleukin-8 production
activin receptor signaling pathway
negative regulation of blood vessel endothelial cell migration
positive regulation of endothelial cell differentiation
positive regulation of Notch signaling pathway
positive regulation of angiogenesis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
blood vessel morphogenesis
cartilage development
positive regulation of SMAD protein import into nucleus
positive regulation of cartilage development
cellular response to BMP stimulus
positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
positive regulation of bicellular tight junction assembly
glucose metabolic process
positive regulation of pathway-restricted SMAD protein phosphorylation
regulation of transforming growth factor beta receptor signaling pathway
neuron differentiation
growth
regulation of apoptotic process
regulation of MAPK cascade
positive regulation of osteoblast differentiation
cell development
pathway-restricted SMAD protein phosphorylation
SMAD protein signal transduction
negative regulation of DNA biosynthetic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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