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Fabgennix
CC2D1A Polyclonal Antibody, Biotin
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Product Details
CC2D1A-BIOTIN
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 850-900 on human Coiled-coil and C2 domain-containing protein 1A protein.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in nonsyndromic mental retardation-3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5-HT1A receptor; Akt kinase-interacting protein 1; Coiled-coil and C2 domain-containing protein 1A; Five prime repressor element under dual repression-binding protein 1; five repressor element under dual repression-binding protein 1; five' repressor element under dual repression binding protein 1; FLJ20241; FRE under dual repression-binding protein 1; freud-1; lethal (2) giant discs homolog 2; Putative NF-kappa-B-activating protein 023N; putative NFkB activating protein; TBK1-associated protein in endolysosomes; unnamed protein product
Gene Aliases: Aki-1; AKI1; BC016188; CC2D1A; FREUD-1; Freud-1/Aki1; LGD2; MRT3; RGD1306108; TAPE
UniProt ID: (Human) Q6P1N0, (Rat) Q66HA5, (Mouse) Q8K1A6
Entrez Gene ID: (Human) 54862, (Rat) 288908, (Mouse) 212139
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
protein binding
cadherin binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
signal transducer activity
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
transcription from RNA polymerase II promoter
signal transduction
positive regulation of I-kappaB kinase/NF-kappaB signaling
regulation of respiratory gaseous exchange by neurological system process
regulation of transcription from RNA polymerase II promoter
endosome organization
regulation of respiratory gaseous exchange
dendrite arborization
apical dendrite arborization
regulation of postsynapse assembly
negative regulation of snRNA transcription by RNA polymerase II
regulation of transcription, DNA-templated
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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