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OriGene
RGL2 Monoclonal Antibody (OTI9H3), TrueMAB™
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FIGURE: 1 / 1
RGL2 Antibody (CF808397) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RGL2 (RC207582, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-RGL2. (1. Positive lysates LY417774 (100 µg) and LC417774 (20 µg) can be purchased separately from OriGene.
Product Details
CF808397
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI9H3
Immunogen
Human recombinant protein fragment corresponding to amino acids 547-777 of human RGL2 produced in E.coli.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
Probable guanine nucleotide exchange factor. Putative effector of Ras and/or Rap. Associates with the GTP-bound form of Rap 1A and H-Ras in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GDS-related protein; RAB2L; ral guanine nucleotide dissociation stimulator,-like 2; Ral guanine nucleotide dissociation stimulator-like 2; RalGDS-like 2; RalGDS-like factor; Ras-associated protein RAB2L; unnamed protein product
Gene Aliases: HKE1.5; KE1.5; RAB2L; RGL2; Rgt2; Rlf
UniProt ID: (Human) O15211, (Mouse) Q61193
Entrez Gene ID: (Human) 5863, (Rat) 294283, (Mouse) 19732
signal transduction
small GTPase mediated signal transduction
Ras protein signal transduction
negative regulation of cardiac muscle cell apoptotic process
regulation of Ral protein signal transduction
positive regulation of protein kinase B signaling
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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