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OriGene
ELF3 Monoclonal Antibody (OTI7H9), TrueMAB™
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FIGURE: 1 / 1
ELF3 Antibody (CF810005) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ELF3 (RC225564, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ELF3. (1. Positive lysates LY426477 (100 µg) and LC426477 (20 µg) can be purchased separately from OriGene.
Product Details
CF810005
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI7H9
Immunogen
Human recombinant protein fragment corresponding to amino acids 175-286 of human ELF3 produced in E.coli.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
ESE-1 (Epithelium-Specific Ets) is a novel, highly tissue-restricted member of the ets transcription factor/oncogene family, which has features distinct from those of any other ets-related factor. ESE-1 binds with high affinity to and transactivates the ets binding site in the promoter of the keratinocyte terminal differentiation marker gene, SPRR2A. ESE-1 is a critical regulator of epithelial cell differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E74-like factor 3; E74-like factor 3 (ets domain transcription factor); E74-like factor 3 (ets domain transcription factor, epithelial-specific ); E74-like factor 3 (ETS domain transcription factor, serine box, epithelial-specific); ELF3; elf3 {ECO:0000312|EMBL:AAH97980.1}; Epithelial-restricted with serine box; Epithelium-restricted Ets protein ESX; Epithelium-specific Ets transcription factor 1; ESE-1; ets domain transcription factor, serine box (epithelial-specific); ETS-related transcription factor Elf-3; jen; RP11-510N19.1; unnamed protein product
Gene Aliases: ELF3; EPR-1; ERT; ESE-1; ESX; JEN
UniProt ID: (Human) P78545, (Mouse) Q3UPW2, (Rat) Q4V7E1
Entrez Gene ID: (Human) 1999, (Mouse) 13710, (Rat) 304815
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription coactivator activity
winged helix/forkhead transcription factor
blastocyst development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
inflammatory response
anatomical structure morphogenesis
cell differentiation
extracellular matrix organization
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
mammary gland involution
transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
embryo development
positive regulation of transcription, DNA-templated
epithelial cell differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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