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OriGene
SMARCD3 Monoclonal Antibody (OTI4G3), TrueMAB™
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Product Details
CF811107
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI4G3
Immunogen
Full length human recombinant protein of human SMARCD3 produced in E.coli.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
BAF60C is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 60 kDa BRG-1/Brm-associated factor subunit C; BAF60C; BRG1-associated factor 60C; chromatin remodeling complex BAF60C subunit; hBAF60c1; hBAF60c2; mammalian chromatin remodeling complex BRG1-associated factor 60C; mBAF60c; MGC111010; SWI/SNF complex 60 kDa subunit C; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3; Swp73-like protein; unnamed protein product
Gene Aliases: 1500001J14Rik; 2210409C08Rik; BAF60C; CRACD3; Rsc6p; SMARCD3
UniProt ID: (Human) Q6STE5, (Mouse) Q6P9Z1
Entrez Gene ID: (Human) 6604, (Mouse) 66993, (Rat) 296732
transcription cofactor binding
chromatin binding
transcription cofactor activity
transcription coactivator activity
receptor binding
protein binding
ligand-dependent nuclear receptor binding
DNA-binding transcription factor binding
transcription factor binding
ligand-dependent nuclear receptor transcription coactivator activity
nuclear hormone receptor binding
chromatin/chromatin-binding, or -regulatory protein
positive regulation of neuroblast proliferation
heart morphogenesis
secondary heart field specification
cardiac right ventricle formation
neural retina development
chromatin organization
nucleosome disassembly
chromatin remodeling
regulation of transcription from RNA polymerase II promoter
nervous system development
positive regulation of G2/M transition of mitotic cell cycle
regulation of mitotic metaphase/anaphase transition
muscle cell differentiation
positive regulation of T cell differentiation
positive regulation of cell differentiation
positive regulation of myoblast differentiation
positive regulation of transcription, DNA-templated
positive regulation of smooth muscle cell differentiation
regulation of G0 to G1 transition
regulation of G1/S transition of mitotic cell cycle
positive regulation of double-strand break repair
regulation of nucleotide-excision repair
transcription, DNA-templated
regulation of transcription, DNA-templated
chromatin modification
regulation of protein binding
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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