Chromeleon™ Chromatography Data System (CDS)

Built to support lab management and system administrators, Thermo Scientific™ Chromeleon™ Chromatography Data System provides flexibility and scalability. Users can manage more than 500+ chromatography instruments (including third-party CEs) and Thermo Scientific single/triple quadrupole and HRAM mass spectrometry instruments in one data system.

The Chromeleon Enterprise Software effectively scales to accommodate over 1000 instruments and seamlessly connects users worldwide within a tiered enterprise system. It incorporates version-controlled data storage in a relational database, ensuring data integrity, and implements logon and role level security with extensive configurable privileges. These features are designed to meet the requirements of GMP and 21 CFR Part 11, making it a reliable and compliant ready solution for regulated industries.

For the Laboratory:

• Digital Chromeleon-native third-party Capillary Electrophoresis (CE) Instrument Control for the SCIEX™ (and Beckman Coulter) PA 800 Plus system
• Ease training requirements with customizable user interface — only see what you need in the contextual ribbons
• Improved productivity with shorter time to results by unblocking UI during reprocessing
• Get rapid access to the information you need utilizing sorting and filtering of your results based on custom conditions
• Benefit from faster result review by flagging outliers like failed calibrations, out-of-spec QC samples, and any sample or compound that yields a positive result via conditional formatting
• Eliminate data transfer errors with comprehensive, yet easy-to-customize new 64-bit Excel-style reporting module enabling the rendering of large reports

Built for the Lab

For the Mass Spectrometry Laboratory:

• Remove the complexity of multiple data systems with one software to control your MS and chromatography instruments with all functionality to support GMP and data integrity regulatory guidelines
• Significantly reduce time from sample to results with faster MS data processing, streamlined data review and built-in report customization
• Benefit from support for MS¹ — MS³ targeted library searching and DDA, MS² and fragment matching targeted quantitation
• Eliminate the need to transfer data with customizable spreadsheet-based reporting with querying for multi-consensus reports and built-in report templates for numerous MS workflows
• Achieve high quality results with support for intact mass deconvolution both isotopically resolved and unresolved
• Gain confidence in results with support for orthogonal cross confirmation (e.g., GC-MS with LC-MS) with simultaneous processing and reporting of two sequences

Built for Mass Spectrometry

For the GMP-regulated Laboratory:

• Full security through version-controlled storage of raw metadata and results in a relational database
• Easier to achieve, maintain, and demonstrate compliance, designed to keep up with ever-evolving standards and regulations
• Map user capabilities directly into Chromeleon Software access rights with highly granular user privileges for the processing method
• More right-first-time results and reduction of out-of-specification results with active sequence approval step before acquisition
• Centralized audit trails with GxP-ready tools to compare changes between results, methods, or in the system all with a sequence-based electronic signature workflow
• Visual before/after comparison of manually integrated runs

Built for Compliance

For IT:

• Reduced network traffic allows for faster identification/location of domain resources in multi-site deployments
• Improve performance and responsiveness for large-scale implementations with incremental redundancy for central administrative tasks
• Faster, error-free execution of large (e.g. HRAM MS/MS) data file transfers using background processing
• Streamlined handling of custom variables offering faster querying and operation of Data Vaults with large numbers
• Reduced costs for faster ROI- Enable standardization of your system to reduce costs with no compromise to additional lab efficiency gains
• Best-in-class network resilience ensuring data security and eliminating single points of failure