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Invitrogen
Vitronectin Monoclonal Antibody (A18)
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Product Details
CSI 004-18-02
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Horse,
Rabbit
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
A18
Immunogen
Lysed bovine corneal endothelial cells and extracellular matrix.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.03 mg/mL
Amount
412 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
15mM sodium azide
Storage conditions
4°C, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
CSI 004-18-02 is highly specific for vitronectin. There is no evidence for cross-reactivity with other connective tissue proteins (fibronectin, elastin, collagen, laminin). CSI 004-18-02 cross-reacts with rabbit and horse vitronectin, no reactivity with human or sheep.
CSI 004-18-02 has been successfully used in ELISA and Immunohistochemistry techniques. CSI 004-18-02 is suitable in ELISA and immunostaining of frozen PLP-fixed sections of bovine tissues.
The antibody inhibits integrin-mediated cell adhesion to bovine vitronectin. It can be used to probe vitronectin conformation.
CSI 004-18-02 reacts weakly in ELISA with vitronectin coated directly onto the microtiter plate.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
Target Information
VTN is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: glycoprotein 66; S-protein; serum-spreading factor; vitronectin (serum spreading factor, somatomedin B, complement S-protein)
Gene Aliases: VN
UniProt ID: (Rabbit) P22458
Entrez Gene ID: (Horse) 100059034, (Bovine) 507525, (Rabbit) 100009128
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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