Search
Citations & References (15)
Invitrogen™
Gelatin From Pig Skin, Fluorescein Conjugate
Molecular Probes™ fluorescent conjugates of gelatin are designed for researchers studying not only collagen-binding proteins and collagen metabolism, but alsoRead more
| Catalog Number | Quantity |
|---|---|
| G13187 | 5 mg |
Catalog number G13187
Price (JPY)Contact Us ›
46,200
Each
Quantity:
5 mg
Molecular Probes™ fluorescent conjugates of gelatin are designed for researchers studying not only collagen-binding proteins and collagen metabolism, but also for the study of gelatinases and collagenases (metalloproteins that digest collagen and gelatin). We offer two fluorescent conjugates of gelatin—one in which gelatin is coupled to fluorescein (G13187) and the other in which gelatin is coupled to our Oregon Green™ 488 dye (G13186).
Gelatin Conjugate Specifications:
• Label (Ex/Em): Fluorescein (∼499/519 nm)
• Degree of labeling is listed on the product label (based on molecular weight of 100,000)
Find More Probes for Following Receptor Binding and Cell Adhesion
Review Probes for Following Receptor Binding and Phagocytosis—Section 16.1 and Probes for Cell Adhesion, Chemotaxis, Multidrug Resistance and Glutathione—Section 15.6 in the Molecular Probes™ Handbook for more information on these products.
For Research Use Only. Not for human or animal therapeutic or diagnostic use.
Gelatin Conjugate Specifications:
• Label (Ex/Em): Fluorescein (∼499/519 nm)
• Degree of labeling is listed on the product label (based on molecular weight of 100,000)
Find More Probes for Following Receptor Binding and Cell Adhesion
Review Probes for Following Receptor Binding and Phagocytosis—Section 16.1 and Probes for Cell Adhesion, Chemotaxis, Multidrug Resistance and Glutathione—Section 15.6 in the Molecular Probes™ Handbook for more information on these products.
For Research Use Only. Not for human or animal therapeutic or diagnostic use.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Label TypeClassic Dyes
Protein SubtypeGelatin
Quantity5 mg
Shipping ConditionRoom Temperature
ConjugateFluorescein
FormLyophilized
SpeciesPig
Unit SizeEach
Contents & Storage
Store in freezer (-5 to -30°C) and protect from light.
Citations & References (15)
Citations & References
Abstract
Matrix architecture dictates three-dimensional migration modes of human macrophages: differential involvement of proteases and podosome-like structures.
Journal:J Immunol
PubMed ID:20018633
'Tissue infiltration of macrophages, although critical for innate immunity, is also involved in pathologies, such as chronic inflammation and cancer. In vivo, macrophages migrate mostly in a constrained three-dimensional (3D) environment. However, in vitro studies, mainly focused on two dimensions, do not provide meaningful clues about the mechanisms involved in
Studies of fibronectin matrices in living cells with fluoresceinated gelatin.
Journal:J Cell Biol
PubMed ID:6998987
'We have used fluorescein isosthiocyanate-conjugated gelatin (FITC-gelatin) (1 mg/ml) to localize cell surface fibronectin in unfixed live cells in cultures. FITC-gelatin stains the fibronectin matrix on primary cultures of rat and chick embryo fibroblasts as well as untransformed, established cell lines. In live cultured cells, fibronectin in many areas of
TLR ligand-induced podosome disassembly in dendritic cells is ADAM17 dependent.
Journal:J Cell Biol
PubMed ID:18762577
Toll-like receptor (TLR) signaling induces a rapid reorganization of the actin cytoskeleton in cultured mouse dendritic cells (DC), leading to enhanced antigen endocytosis and a concomitant loss of filamentous actin-rich podosomes. We show that as podosomes are lost, TLR signaling induces prominent focal contacts and a transient reduction in DC
Fluid-phase interaction between human plasma fibronectin and gelatin determined by fluorescence polarization assay.
Journal:Arch Biochem Biophys
PubMed ID:6364982
Previous studies of the binding properties of fibronectin (Fn) have utilized methods whereby one or the other macromolecule was immobilized on a solid phase. In order to examine the interaction between human plasma Fn and gelatin in solution, the latter was labeled with fluorescein isothiocyanate (FITC) whose fluorescence polarization (P)
Pathophysiology of premature skin aging induced by ultraviolet light.
Journal:N Engl J Med
PubMed ID:9358139
BACKGROUND: Long-term exposure to ultraviolet irradiation from sunlight causes premature skin aging (photoaging), characterized in part by wrinkles, altered pigmentation, and loss of skin tone. Photoaged skin displays prominent alterations in the collagenous extracellular matrix of connective tissue. We investigated the role of matrix-degrading metalloproteinases, a family of proteolytic enzymes,