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Abnova
DLX3 Polyclonal Antibody, MaxPab™
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Product Details
H00001747-D01P
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DLX3 (NP_005211.1, 1 a.a. approximately 287 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MSGSFDRKLS SILTDISSSL SCHAGSKDSP TLPESSVTDL GYYSAPQHDY YSGQPYGQTV NPYTYHHQFN LNGLAGTGAY SPKSEYTYGA SYRQYGAYRE QPLPAQDPVS VKEEPEAEVR MVNGKPKKVR KPRTIYSSYQ LAALQRRFQK AQYLALPERA ELAAQLGLTQ TQVKIWFQNR RSKFKKLYKN GEVPLEHSPN NSDSMACNSP PSPALWDTSS HSTPAPARSQ LPPPLPYSAS PSYLDDPTNS WYHAQNLSGP HLQQQPPQPA TLHHASPGPP PNPGAVY
Target Information
The distal-less homeobox 3 (DLX3) protein is a putative transcriptional activator that has been implicated during development and differentiation of epithelial tissues. This is a homeodomain transcription factor in vertebrates, related to Distal-less in Drosophila, which is expressed in differentiating epidermal cells, in neural crest, hair follicles, dental epithelium, mesenchyme, the optic and olfactory placodes, limb bud, placenta, and in the cement gland, which is located in the extreme anterior neural plate in Xenopus embryos.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DII C; Homeobox protein DLX-3; unnamed protein product
Gene Aliases: AI4; AV237891; Dlx-3; DLX3; TDO
UniProt ID: (Human) O60479, (Mouse) Q64205
Entrez Gene ID: (Human) 1747, (Mouse) 13393
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
sequence-specific double-stranded DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
sequence-specific DNA binding
homeodomain transcription factor
blood vessel development
placenta development
hair follicle development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
gene expression
Wnt signaling pathway
BMP signaling pathway
epithelial cell differentiation
hair follicle morphogenesis
hair cell differentiation
odontogenesis of dentin-containing tooth
hair cycle
positive regulation of transcription from RNA polymerase II promoter
embryonic skeletal system development
hair follicle cell proliferation
odontoblast differentiation
transcription from RNA polymerase II promoter
multicellular organism development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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