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Abnova
DSCR1 Polyclonal Antibody, MaxPab™
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Product Details
H00001827-B01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DSCR1 (NP_981962.1, 1 a.a. approximately 117 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Amount
50 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MKLYFAQTLH IGSSHLAPPN PDKQFLISPP ASPPVGWKQV EDATPVINYD LLYAISKLGP GEKYELHAAT DTTPSVVVHV CESDQEKEEE EEMERMRRPK PKIIQTRRPE YTPIHLS
Target Information
The RCAN1 protein interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADAPT78; calcineurin inhibitor; CALP1L; Calcipressin-1; calcium and oxidant-inducible mRNA; Down syndrome candidate region 1; down syndrome candidate region 1; one of four alternatively spliced exon 1; Down syndrome critical region gene 1; Down syndrome critical region protein 1; DSCR1; MCIP1; modulatory calcineurin-interacting protein 1; Myocyte-enriched calcineurin-interacting protein 1; near DSCR proline-rich protein; Regulator of calcineurin 1; unnamed protein product
Gene Aliases: ADAPT78; CSP1; DSC1; DSCR1; MCIP1; RCAN1; RCN1
UniProt ID: (Human) P53805
Entrez Gene ID: (Human) 1827
response to ischemia
response to stress
response to oxidative stress
skeletal muscle tissue development
short-term memory
response to mechanical stimulus
calcium-mediated signaling
locomotion involved in locomotory behavior
calcineurin-NFAT signaling cascade
response to estrogen
skeletal muscle fiber development
negative regulation of smooth muscle cell differentiation
negative regulation of calcineurin-NFAT signaling cascade
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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