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Abnova
RANBP5 Monoclonal Antibody (1C4)
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Product Details
H00003843-M01
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
1C4
Immunogen
RANBP5 (AAH01497, 1 a.a. approximately 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.42 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MAAAAAEQQQ FYLLLGNLLS PDNVVRKQAE ETYENIPGQS KITFLLQAIR NTTAAEEARQ MAAVLLRRLL SSAFDEVYPA LPSDVQTAIK SELLMIIQME
Target Information
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Imp5; importin 5; importin beta-3 subunit; Importin subunit beta-3; Importin-5; IPO 5; Kap beta3 import receptor; karyopherin (importin) beta 3; Karyopherin beta 3; Karyopherin beta-3; MGC2068; PSE1 homolog; RAN binding protein 5; Ran-binding protein 5; Ran_GTP binding protein 5; RanBP 5; RanBP5; unnamed protein product
Gene Aliases: 1110011C18Rik; 5730478E03Rik; AA409333; C76941; IMB3; imp5; IPO5; KPNB3; Pse1; RANBP5
UniProt ID: (Human) Q5T578, (Mouse) Q8BKC5
Entrez Gene ID: (Human) 3843, (Rat) 306182, (Mouse) 70572
cytoplasmic pattern recognition receptor signaling pathway
protein import into nucleus
NLS-bearing protein import into nucleus
ribosomal protein import into nucleus
intracellular protein transport
protein transport
positive regulation of protein import into nucleus
negative regulation of cell cycle
cellular response to amino acid stimulus
transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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