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Abnova
SLC2A4 Monoclonal Antibody (2A4)
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Product Details
H00006517-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
2A4
Immunogen
SLC2A4 (NP_001033, 467 a.a. approximately 509 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: RVPETRGRTF DQISAAFHRT PSLLEQEVKP STELEYLGPD END
Target Information
This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: glucose transporter glut4; Glucose transporter type 4, insulin-responsive; GLUT-4; insulin-responsive glucose transporter; insulin-responsive glucose transporter type 4; MGC93607; solute carrier family 2 (facilitated glucose transporter), member 4; Solute carrier family 2, facilitated glucose transporter member 4; unnamed protein product
Gene Aliases: GLUT4; SLC2A4
UniProt ID: (Human) P14672
Entrez Gene ID: (Human) 6517
carbohydrate metabolic process
learning or memory
short-term memory
long-term memory
amylopectin biosynthetic process
positive regulation of brain-derived neurotrophic factor receptor signaling pathway
cellular response to insulin stimulus
glucose homeostasis
glucose import in response to insulin stimulus
response to ethanol
glucose import
brown fat cell differentiation
transmembrane transport
white fat cell proliferation
dehydroascorbic acid transport
cellular response to tumor necrosis factor
cellular response to hypoxia
cellular response to osmotic stress
regulation of synaptic vesicle budding from presynaptic endocytic zone membrane
transport across blood-brain barrier
glucose transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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