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Abnova
TMEM1 Monoclonal Antibody (5D5)
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Product Details
H00007109-M02
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
5D5
Immunogen
TMEM1 (NP_003265, 1162 a.a. approximately 1257 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: VRLFKYLPHH SAHSSQLDAD SWIENDSLSV DKHGDDQPDS SSLKSRGSVH SACSSEHKGL PMPRLQALPA GQVFNSSSGT QVLVIPSQDD HVLEVS
Target Information
TRAPPC10, also known as TMEM1 (transmembrane protein 1), EHOC1 (epilepsy holoprosencephaly candidate 1 protein) or GT334, is a widely expressed 1,259 amino acid protein that may function in vesicular transport. Despite its name, TRAPPC10 does not contain transmembrane domains. It is the human ortholog of the yeast Trs130 protein and its structure and function appears to be conserved. Localizing to the cis-Golgi apparatus, TRAPPC10 is believed to be involved in transport from the endoplasmic reticulum (ER) to the Golgi functioning as a component of the multisubunit transport protein particle (TRAPP) complex. Mutations in the gene encoding TRAPPC10 may be involved in autoimmune polyglandular disease type 1 or Unverricht-Lundborg disease, an autosomal recessive type of progressive myoclonic epilepsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EHOC-1; Epilepsy holoprosencephaly candidate 1 protein; epilepsy holoprosencephaly candidate-1 protein; Protein GT334; putative transmembrane protein; trafficking protein particle complex 10; Trafficking protein particle complex subunit 10; trafficking protein particle complex subunit 130; Trafficking protein particle complex subunit TMEM1; transmembrane protein 1; Transport protein particle subunit TMEM1; TRAPP 130 kDa subunit; TRAPP subunit TMEM1; unnamed protein product
Gene Aliases: EHOC-1; EHOC1; GT334; NEDMISS; TMEM1; TRAPPC10; TRS130; TRS30
UniProt ID: (Human) P48553
Entrez Gene ID: (Human) 7109
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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