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Abnova
YWHAH Monoclonal Antibody (1C2)
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Product Details
H00007533-M07
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
1C2
Immunogen
YWHAH (AAH03047, 71 a.a. approximately 170 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Immunogen sequence: MADGNEKKLE KVKAYREKIE KELETVCNDV LSLLDKFLIK NCNDFQYESK VFYLKMKGDY YRYLAEVASG EKKNSVVEAS EAAYKEAFEI SKEQMQPTHP
Target Information
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 14-3-3 eta; 14-3-3 protein eta; 14-3-3n; 1433F; AS1; brain-specific tyrosine and tryptophan hydroxylase activator; Protein AS1; similar to Homo sapiens DNA for 14-3-3 protein eta chain, exon 2 with GenBank Accession Number D78577.1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; unnamed protein product; YWHA114-3-3 eta; YWHAH
Gene Aliases: YWHA1; YWHAH
UniProt ID: (Human) Q04917
Entrez Gene ID: (Human) 7533
regulation of sodium ion transport
glucocorticoid catabolic process
intracellular protein transport
signal transduction
protein localization
substantia nigra development
glucocorticoid receptor signaling pathway
regulation of neuron differentiation
positive regulation of transcription, DNA-templated
regulation of synaptic plasticity
negative regulation of dendrite morphogenesis
membrane depolarization during action potential
presynaptic modulation of chemical synaptic transmission
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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