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Abnova
DCPS Polyclonal Antibody, MaxPab™
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Product Details
H00028960-D01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DCPS (NP_054745.1, 1 a.a. approximately 337 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MADAAPQLGK RKRELDVEEA HAASTEEKEA GVGNGTCAPV RLPFSGFRLQ KVLRESARDK IIFLHGKVNE ASGDGDGEDA VVILEKTPFQ VEQVAQLLTG SPELQLQFSN DIYSTYHLFP PRQLNDVKTT VVYPATEKHL QKYLRQDLRL IRETGDDYRN ITLPHLESQS LSIQWVYNIL DKKAEADRIV FENPDPSDGF VLIPDLKWNQ QQLDDLYLIA ICHRRGIRSL RDLTPEHLPL LRNILHQGQE AILQRYRMKG DHLRVYLHYL PSYYHLHVHF TALGFEAPGS GVERAHLLAE VIENLECDPR HYQQRTLTFA LRADDPLLKL LQEAQQS
Target Information
Necessary for the complete degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA fragments shorter than 10 nucleotides that are produced by 3'->5' exosome-mediated mRNA decay. Releases m7GMP. Can also degrade m7GDP to m7GMP. Has no activity towards mRNA molecules longer than 25 nucleotides.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase; DCPS; DCS-1; Decapping scavenger enzyme; epididymis secretory sperm binding protein; heat shock-like protein 1; HINT-5; Hint-related 7meGMP-directed hydrolase; Histidine triad nucleotide-binding protein 5; Histidine triad protein member 5; homolog of C. elegans 7meGMP-directed hydrolase dcs-1; m7GpppX diphosphatase; mRNA decapping enzyme; NADPH-dependent flavin reductase; Scavenger mRNA-decapping enzyme DcpS
Gene Aliases: 1700001E16Rik; AA408441; ARS; DCPS; DCS1; HINT-5; HINT5; HSL1; HSPC015
UniProt ID: (Human) Q96C86, (Mouse) Q9DAR7
Entrez Gene ID: (Human) 28960, (Mouse) 69305
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
deadenylation-dependent decapping of nuclear-transcribed mRNA
mRNA processing
RNA splicing
mRNA cis splicing, via spliceosome
mRNA methylguanosine-cap decapping
cellular response to menadione
negative regulation of programmed cell death
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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