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Invitrogen
Calcitonin Monoclonal Antibody (13B9)
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FIGURE: 1 / 2
Calcitonin Antibody (MA1-20285) in WB
Detection of human recombinant PCT in Western blotting by monoclonal antibodies specific to calcitonin following 15% SDS-PAGE in reducing conditions. Antigen loaded - 100 ng/lane; Lane 1: Calcitonin Monoclonal Antibody (13B9) (Product # MA1-20285); Lane 2: Calcitonin Monoclonal Antibody (13f2) (Product # MA1-20890); Lane 3: Calcitonin antibody [13G11] (Product # MA1-20891); Lane 4: Calcitonin antibody [14A2] (Product # MA1-20290); Lane 5: Calcitonin antibody [16B5] (Product # MA1-20288); Lane 6: Calcitonin Monoclonal Antibody (24B2) (Produ... View More
Product Details
MA1-20285
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
13B9
Immunogen
Calcitonin conjugated with carrier protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
5.0 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody may be used in a sandwich ELISA when paired with MA1-20291 as the capture antibody.
Target Information
Calcitonin is a 32 amino acid peptide which can be demonstrated in C cells of the normal and hyperplastic thyroid. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha CGRP; Alpha type CGRP; Alpha-type CGRP; Calcitonin; calcitonin 1; calcitonin gene related peptide 1; calcitonin gene related protein; Calcitonin gene-related peptide 1; Calcitonin gene-related peptide I; calcitonin precursor; calcitonin/calcitonin-related polypeptide, alpha; CGRP-I; CGRP1; katacalcin; katacalcin (KC); unnamed protein product
Gene Aliases: CALC1; CALCA; CGRP; CGRP-alpha; CGRP-I; CGRP1; CT; KC; PCT
UniProt ID: (Human) P06881
Entrez Gene ID: (Human) 796
response to yeast
endothelial cell proliferation
vasculature development
neurological system process involved in regulation of systemic arterial blood pressure
G-protein coupled receptor internalization
monocyte chemotaxis
protein phosphorylation
leukocyte cell-cell adhesion
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
cell-cell signaling
embryo implantation
regulation of blood pressure
negative regulation of calcium ion transport into cytosol
antibacterial humoral response
antifungal humoral response
receptor internalization
activation of protein kinase activity
positive regulation of interleukin-1 alpha production
positive regulation of interleukin-8 production
vasodilation
endothelial cell migration
innate immune response
positive regulation of macrophage differentiation
negative regulation of osteoclast differentiation
negative regulation of blood pressure
negative regulation of bone resorption
negative regulation of transcription, DNA-templated
negative regulation of smooth muscle contraction
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
regulation of cytosolic calcium ion concentration
antimicrobial humoral immune response mediated by antimicrobial peptide
cellular response to tumor necrosis factor
calcitonin family receptor signaling pathway
amylin receptor 1 signaling pathway
amylin receptor 2 signaling pathway
cellular response to nerve growth factor stimulus
calcitonin gene-related peptide receptor signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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