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Invitrogen
Myeloperoxidase Monoclonal Antibody (2C7)
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FIGURE: 1 / 7
Myeloperoxidase Antibody (MA1-80878) in ICC/IF
Immunofluorescence analysis of MPO was performed using HL-60 and Jurkat cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. HL-60 and Jurkat cells were labeled with Myeloperoxidase Monoclonal Antibody (2C7) (Product # MA1-80878) at 1:100 dilution in 0.1% BSA, incubated at 4 degree C... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA1-80878
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2C7
Immunogen
Human Myeloperoxidase.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
200 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody does not react with rat.
Non-reducing conditions are recommended for Western blot applications. A suggested positive control for immunohistochemical applications is bone marrow.
Mouse anti Human myeloperoxidase antibody, clone 2C7 recognizes human myeloperoxidase (MPO).
Target Information
Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme is responsible for producing hypohalous acids that are central to the microbicidal activity of neutrophils. Diseases that are associated with MPO include Myeloperoxidase Deficiency and Alzheimer's Disease, Familial, 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
nucleosome disassembly
defense response
response to oxidative stress
response to mechanical stimulus
thiocyanate metabolic process
response to food
response to lipopolysaccharide
low-density lipoprotein particle remodeling
defense response to bacterium
hydrogen peroxide catabolic process
negative regulation of apoptotic process
neutrophil-mediated killing of symbiont cell
neutrophil mediated killing of bacterium
neutrophil mediated killing of fungus
cellular oxidant detoxification
neutrophil extracellular trap formation
positive regulation of cholesterol import
response to gold nanoparticle
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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