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MA1-82669 recognizes an antigen expressed by human macrophages monocytes and histiocytes, but does not stain interdigitating dendritic cells, Langerhans cells, microglial cells or lymphoid cells. Some staining of basophilic granulocytes and of mast cells may be seen. In immunohistochemical studies, the antibody shows partial cross-blocking with some anti-CD68 monoclonal antibodies, suggesting that the epitope may be associated with this antigen.
Heat-mediated antigen retrieval using a sodium citrate buffer (pH 6.0) is recommended for the staining of paraffin sections. A suggested positive control for immunohistochemical applications is spleen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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