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Invitrogen
C/EBP beta Monoclonal Antibody (1H7)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA1-827
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Published species
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
1H7
Immunogen
Recombinant mouse LIP.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS with 1mg/mL BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA1-827 detects C/EBP beta protein in mouse and rat samples. MA1-827 detects the LAP*, LAP and LIP isoforms of C/EBP beta.
MA1-827 has successfully been used in Western blot, immunofluorescent and immunoprecipitation procedures. By Western blot, this antibody detects 38, 35 and 20 kDa proteins representing C/EBP beta LAP*, LAP, and LIP isoforms respectively, in 3T3-L1 cells. LIP is recognized as the C-terminus fragment. Immunofluorescent staining of C/EBP beta in P388D1 cells can be performed using MA1-827
The MA1-827 immunogen is recombinant mouse LIP.
Target Information
This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of mesenchymal tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: AGP/EBP; C EBP; C/EBP BETA; CCAAT/enhancer binding protein (C/EBP), beta; IL-6DBP; interleukin-6-dependent-binding protein; liver-enriched transcriptional activator; nuclear factor-IL6; nuclear protein Il6; OTTMUSP00000017503; SF-B; silencer factor B; unnamed protein product
Gene Aliases: C/EBPbeta; CRP2; IL-6DBP; Il6dbp; LAP; LIP; NF-IL6; NF-M; Nfil6; TCF5
UniProt ID: (Mouse) P28033, (Rat) P21272
Entrez Gene ID: (Mouse) 12608, (Rat) 24253
transcription regulatory region sequence-specific DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
kinase binding
chromatin DNA binding
histone acetyltransferase binding
glucocorticoid receptor binding
identical protein binding
protein homodimerization activity
histone deacetylase binding
sequence-specific DNA binding
ubiquitin-like protein ligase binding
protein heterodimerization activity
RNA polymerase II sequence-specific DNA binding transcription factor binding
DNA-binding transcription factor binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
ovarian follicle development
liver development
embryonic placenta development
granuloma formation
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
memory
positive regulation of gene expression
neuron differentiation
response to lipopolysaccharide
regulation of interleukin-6 production
positive regulation of interleukin-4 production
mammary gland epithelial cell proliferation
response to endoplasmic reticulum stress
T-helper 1 cell activation
negative regulation of T cell proliferation
defense response to bacterium
negative regulation of neuron apoptotic process
fat cell differentiation
regulation of cell differentiation
positive regulation of fat cell differentiation
positive regulation of osteoblast differentiation
regulation of osteoclast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of inflammatory response
brown fat cell differentiation
mammary gland epithelial cell differentiation
myeloid cell development
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
positive regulation of biomineral tissue development
cellular response to lipopolysaccharide
cellular response to amino acid stimulus
cellular response to interleukin-1
hepatocyte proliferation
liver regeneration
positive regulation of cold-induced thermogenesis
regulation of odontoblast differentiation
positive regulation of sodium-dependent phosphate transport
regulation of dendritic cell differentiation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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