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Invitrogen
PLK1 Antibody Cocktail
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA1-90827
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Mouse
/ IgG, kappa
Class
Cocktail
Type
Antibody
Clone
Mixed clones
Immunogen
Fusion protein: DPACIPIFWVS KWVDYSDKYG LGYQLCDNS VGVLFNDST RLILYNDGDSL QYIERDGTESY LTVSSHPNSLM KKITLLKYFRN YMSEHLLKAGA NITPREGDELA RLPYLRTWF RTRSAIILH LSNGSVQINFF QDHTKLILCP LMAAVTYIDE KRDFRTYRLS LLEEYGCCKE LASRLRYARTM VDKLLSSRSAS NRLKAS, corresponding to amino acids 402-603 of Human Plk1
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
Product Specific Information
MA1-90827 detects Plk1 from human samples.
MA1-90827 has been successfully used in immunofluorescence, immunoprecipitation, Western blot applications.
The MA1-90827 immunogen is a fusion protein: DPACIPIFWVS KWVDYSDKYG LGYQLCDNS VGVLFNDST RLILYNDGDSL QYIERDGTESY LTVSSHPNSLM KKITLLKYFRN YMSEHLLKAGA NITPREGDELA RLPYLRTWF RTRSAIILH LSNGSVQINFF QDHTKLILCP LMAAVTYIDE KRDFRTYRLS LLEEYGCCKE LASRLRYARTM VDKLLSSRSAS NRLKAS, corresponding to amino acids 402-603 of Human Plk1.
Target Information
PLK1 is a serine/threonine kinase that is thought to function in cell mitosis and regarded as a marker of cell proliferation. It has been found to play a critical role in carcinogenesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, CCNB1, CDC25C, CEP55, ECT2, ERCC6L, FBXO5/EMI1, FOXM1, KIF20A/MKLP2, CENPU, NEDD1, NINL, NPM1, NUDC, PKMYT1/MYT1, KIZ, PPP1R12A/MYPT1, PRC1, RACGAP1/CYK4, SGOL1, STAG2/SA2, TEX14, TOPORS, p73/TP73, TPT1 and WEE1. Plays a key role in centrosome functions and the assembly of bipolar spindles by phosphorylating KIZ, NEDD1 and NINL.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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