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          • Primary Antibodies ›
          • TOP2A Antibodies
          The product (cat # {{productObj.productId}}) that you're looking for has been discontinued and replaced with {{productObj.replacementProductId}}. The product (cat # {{productObj.productId}}) that you're looking for has been discontinued. Please contact Technical Support with any questions.

          Invitrogen

          TOP2A Monoclonal Antibody (Ki-S1)

          Advanced Verification
          8 References
          View all (53) TOP2A antibodies

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          Cite TOP2A Monoclonal Antibody (Ki-S1)

          Additional Information:
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          • Antibody Testing Data (3)
          • Advanced Verification (1)
          TOP2A Antibody in Immunohistochemistry (IHC)
          Group 53 Created with Sketch.
          TOP2A Antibody in Immunohistochemistry (IHC)
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          TOP2A Antibody (MA5-12433) in IHC

          Formalin-fixed, paraffin-embedded human tonsil stained with Topoisomerase II using peroxidase-conjugate and AEC chromogen. Note nuclear staining of proliferating cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          TOP2A Antibody in Immunohistochemistry (IHC)
          TOP2A Antibody in Western Blot (WB)
          TOP2A Antibody in Western Blot (WB)
          TOP2A Antibody

          Product Details

          MA5-12433

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500
          -

          Immunohistochemistry (IHC)

          -
          View 6 publications 6 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:400
          View 2 publications 2 publications
          Product Specifications

          Published species

          Human

          Host/Isotype

          Mouse / IgG2a, kappa

          Class

          Monoclonal

          Type

          Antibody

          Clone

          Ki-S1

          Immunogen

          Lysate of the human histiocytic leukemia cell line U937

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Storage conditions

          4°C

          Shipping conditions

          Wet ice

          RRID

          AB_10985950

          Product Specific Information

          MA5-12433 targets Topoisomerase II alpha in IHC (P) applications and shows reactivity with Human samples.

          The MA5-12433 immunogen is lysate of the human histiocytic leukemia cell line U937.

          Target Information

          Topo II alpha plays important roles in synthesis and transcription of DNA as well as chromosomal segregation during mitosis. It is reported to be a sensitive and specific marker of late S-, G2 and M-phases in transformed and developmentally regulated normal cellsTopo II alpha is also implicated in drug resistance of tumor cells.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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