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          • Primary Antibodies ›
          • Cytokeratin 17 Antibodies
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          Invitrogen

          Cytokeratin 17 Monoclonal Antibody (E3)

          1 Published Figure
          9 References
          View all (50) Cytokeratin 17 antibodies

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          Cite Cytokeratin 17 Monoclonal Antibody (E3)

          Additional Information:
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          • Antibody Testing Data (2)
          • Published Figures (1)
          Cytokeratin 17 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          Cytokeratin 17 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          Cytokeratin 17 Antibody (MA5-13539) in IHC (P)

          Formalin-fixed, paraffin-embedded human squamous cell carcinoma stained with Keratin 17 antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Cytokeratin 17 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Cytokeratin 17 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Cytokeratin 17 Antibody in Immunohistochemistry (IHC)

          Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

          Cytokeratin 17 Monoclonal Antibody (E3)

          Product Details

          MA5-13539

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (IHC)

          -
          View 9 publications 9 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:40-1:80
          -
          Product Specifications

          Species Reactivity

          Human, Rat

          Published species

          Human, Mouse

          Host/Isotype

          Mouse / IgG2b, kappa

          Class

          Monoclonal

          Type

          Antibody

          Clone

          E3

          Immunogen

          Keratin preparation from rat enterocytes
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          Conc. Not Determined

          Storage buffer

          tissue culture supernatant

          Contains

          0.09% sodium azide

          Storage conditions

          4°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_10980102

          Product Specific Information

          MA5-13539 targets Cytokeratin 17 in IF and IHC (P) applications and shows reactivity with Human and Rat samples.

          The MA5-13539 immunogen is keratin preparation from rat enterocytes.

          Target Information

          Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately40 kDa and approximately68 kDa and isoelectric pH between 4. 9 - 7. 8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: CK-17; CK17; cytokeratin-17; hard keratin; HLA-DRB1-restricted epitope S1; HLA-DRB1-restricted epitope S2; HLA-DRB1-restricted epitope S3; HLA-DRB1-restricted epitope S4; K17; keratin 17, type I; type I keratin KA17; unnamed protein product

          View more View less

          Gene Aliases: 39.1; CK-17; K17; Ka17; PC2; PCHC1

          View more View less

          UniProt ID: (Human) Q04695, (Rat) Q6IFU8

          View more View less

          Entrez Gene ID: (Human) 3872, (Rat) 287702

          View more View less

          Function(s)
          structural molecule activity protein binding structural constituent of epidermis structural constituent of cytoskeleton
          Process(es)
          morphogenesis of an epithelium positive regulation of cell growth epithelial cell differentiation hair follicle morphogenesis intermediate filament organization positive regulation of translation positive regulation of hair follicle development keratinization intermediate filament-based process
          It has to be done as per old AB suggested Products section.

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