c-Abl Monoclonal Antibody (8E9)

nucleotide binding magnesium ion binding four-way junction DNA binding bubble DNA binding phosphotyrosine binding DNA binding transcription coactivator activity actin monomer binding nicotinate-nucleotide adenylyltransferase activity protein kinase activity protein serine/threonine kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein kinase C binding protein binding ATP binding enzyme activator activity kinase activity transferase activity enzyme binding protein kinase binding protein domain specific binding syntaxin binding manganese ion binding neuropilin binding SH2 domain binding protein serine/threonine kinase activator activity metal ion binding ephrin receptor binding actin filament binding mitogen-activated protein kinase binding proline-rich region binding delta-catenin binding supercoiled DNA binding sequence-specific double-stranded DNA binding

mitotic cell cycle neural tube closure B-1 B cell homeostasis immune effector process B cell proliferation involved in immune response transitional one stage B cell differentiation immune response-activating cell surface receptor signaling pathway DNA repair mismatch repair regulation of transcription, DNA-templated endocytosis phagocytosis autophagy apoptotic process cellular response to DNA damage stimulus response to oxidative stress cell adhesion epidermal growth factor receptor signaling pathway positive regulation of cytosolic calcium ion concentration integrin-mediated signaling pathway I-kappaB kinase/NF-kappaB signaling learning or memory associative learning intrinsic apoptotic signaling pathway in response to DNA damage response to xenobiotic stimulus post-embryonic development regulation of gene expression regulation of autophagy positive regulation of macromolecule biosynthetic process positive regulation of endothelial cell migration cerebellum morphogenesis negative regulation of cell-cell adhesion microspike assembly actin cytoskeleton organization actin filament polymerization regulation of endocytosis regulation of cell adhesion neuron differentiation BMP signaling pathway negative regulation of BMP signaling pathway regulation of axon extension phospholipase C-inhibiting G-protein coupled receptor signaling pathway regulation of microtubule polymerization regulation of Cdc42 protein signal transduction positive regulation of interferon-gamma production positive regulation of interleukin-2 production regulation of actin cytoskeleton organization cellular response to stress positive regulation of osteoblast proliferation substrate adhesion-dependent cell spreading cellular response to oxidative stress response to endoplasmic reticulum stress intracellular signal transduction platelet-derived growth factor receptor-beta signaling pathway protein modification process Fc-gamma receptor signaling pathway involved in phagocytosis neuropilin signaling pathway B cell proliferation regulation of cell proliferation signal transduction in response to DNA damage positive regulation of apoptotic process positive regulation of I-kappaB kinase/NF-kappaB signaling positive regulation of neuron apoptotic process endothelial cell migration regulation of T cell differentiation regulation of cell differentiation positive regulation of cell adhesion positive regulation of vasoconstriction negative regulation of mitotic cell cycle positive regulation of mitotic cell cycle positive regulation of transcription from RNA polymerase II promoter alpha-beta T cell differentiation platelet-derived growth factor receptor signaling pathway ephrin receptor signaling pathway positive regulation of fibroblast proliferation spleen development thymus development activated T cell proliferation T cell receptor signaling pathway B cell receptor signaling pathway neuromuscular process controlling balance positive regulation of release of sequestered calcium ion into cytosol neuron apoptotic process negative regulation of ubiquitin-protein transferase activity myoblast proliferation positive regulation of stress fiber assembly establishment of localization in cell regulation of cell cycle mitochondrial depolarization positive regulation of focal adhesion assembly Bergmann glial cell differentiation cardiac muscle cell proliferation neuroepithelial cell differentiation cellular response to hydrogen peroxide ERK1 and ERK2 cascade negative regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade DNA conformation change cellular response to lipopolysaccharide cellular response to transforming growth factor beta stimulus response to epinephrine circulatory system development positive regulation of cell migration involved in sprouting angiogenesis cellular senescence vascular endothelial cell response to oscillatory fluid shear stress cell-cell adhesion regulation of postsynaptic specialization assembly positive regulation of phospholipase C/protein kinase C signal transduction positive regulation of dendrite development positive regulation of substrate adhesion-dependent cell spreading negative regulation of long-term synaptic potentiation cellular response to oxygen-containing compound regulation of hematopoietic stem cell differentiation regulation of intracellular signal transduction regulation of extracellular matrix organization positive regulation of extracellular matrix organization glomerular visceral epithelial cell apoptotic process cellular response to dopamine positive regulation of establishment of T cell polarity DN4 thymocyte differentiation protein localization to cytoplasmic microtubule plus-end regulation of modification of synaptic structure positive regulation of blood vessel branching negative regulation of double-strand break repair via homologous recombination positive regulation of Wnt signaling pathway, planar cell polarity pathway regulation of cell motility negative regulation of endothelial cell apoptotic process positive regulation of T cell migration regulation of cellular senescence negative regulation of cellular senescence