Search
Invitrogen
GRP94 Monoclonal Antibody (9G10.F8.2), Biotin
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 6
GRP94 Antibody (MA5-14589) in WB
Western blot analysis was performed on membrane enriched extracts (30 µg lysate) of U-87 MG (Lane 1), T-47D (Lane 2), MCF-7 (Lane 3), HeLa (Lane 4), HAEC (Lane 5), SW480 (Lane 6), A-549 (Lane 7) and tissue extracts of Mouse Lung (Lane 8). The blot was probed with Anti-GRP94 Rat Monoclonal Antibody, Biotin (Product # MA5-14589, 1 µg/mL) and detected by chemiluminescence. A 92 kDa band corresponding to GRP94 was observed across the cell lines tested. Known quantity of protein samples were electrophoresed using Novex® NuPAGE® 10% Bis-Tris gel... View More
Product Details
MA5-14589
Applications
Tested Dilution
Publications
Product Specifications
Published species
Human,
Mouse
Host/Isotype
Rat
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
9G10.F8.2
Immunogen
Purified glucose regulated protein 94 (grp94) from chicken oviducts
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
100 µg
Storage conditions
4°C
Shipping conditions
Wet ice
RRID
Product Specific Information
MA5-14589 targets Glucose-Regulated Protein 94 in IHC (P), IP, and WB applications and shows reactivity with Bovine, Canine, Chicken, Equine, Guinea Pig, Hamster, Human, mouse, Non-human primate, Ovine, Porcine, Rabbit, Rat, and Xenopus laevis samples.
The MA5-14589 immunogen is purified glucose regulated protein 94 (grp94) from chicken oviducts.
Target Information
GRP94 is a 803 amino acid protein belonging to the heat shock protein 90 family. It acts as a molecular chaperone that functions in the processing and transport of secreted proteins. GRP94 and its N-terminal fragment stimulates CTL expansion and maturation of human monocyte-derived dendritic cells (MDDC). It plays a central role in innate as well as acquired immunity, maturation and chemotaxis of dendritic cells, Ab production, cross-priming, as a potential marker in breast cancer and is a peptide acceptor in endoplasmic reticulum and an accessory to peptide loading of MHC class I molecules. Expression of GRP94 suppressed A23187-induced apoptosis and stabilized calcium homeostasis. GRP94 is expressed in melanoma or liver metastases of colon carcinoma cells, human gastric carcinoma BGC-823 cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support