ERK1/ERK2 Monoclonal Antibody (K.913.4)

phosphotyrosine binding protein serine/threonine kinase activity MAP kinase kinase activity ATP binding RNA polymerase II carboxy-terminal domain kinase activity phosphatase binding identical protein binding nucleotide binding DNA binding protein kinase activity MAP kinase activity protein binding kinase activity transferase activity protein serine kinase activity DNA-binding transcription factor binding transcription factor binding protein kinase binding mitogen-activated protein kinase kinase kinase binding transferase activity, transferring phosphorus-containing groups scaffold protein binding non-receptor serine/threonine protein kinase

activation of MAPK activity protein phosphorylation apoptotic process cellular response to DNA damage stimulus cell cycle positive regulation of gene expression positive regulation of peptidyl-threonine phosphorylation peptidyl-serine phosphorylation peptidyl-threonine phosphorylation cytosine metabolic process regulation of ossification regulation of cellular pH thyroid gland development regulation of protein stability lipopolysaccharide-mediated signaling pathway positive regulation of telomere maintenance via telomerase mammary gland epithelial cell proliferation cellular response to amino acid starvation cellular response to reactive oxygen species response to nicotine ERBB signaling pathway outer ear morphogenesis response to exogenous dsRNA negative regulation of cell differentiation thymus development T cell receptor signaling pathway B cell receptor signaling pathway stress-activated MAPK cascade positive regulation of telomerase activity Bergmann glial cell differentiation long-term synaptic potentiation face development lung morphogenesis trachea formation labyrinthine layer blood vessel development cardiac neural crest cell development involved in heart development ERK1 and ERK2 cascade response to epidermal growth factor cellular response to cadmium ion cellular response to tumor necrosis factor cellular response to granulocyte macrophage colony-stimulating factor stimulus cellular response to dopamine positive regulation of telomere capping MAPK cascade regulation of transcription from RNA polymerase II promoter chemotaxis signal transduction cell surface receptor signaling pathway epidermal growth factor receptor signaling pathway chemical synaptic transmission heart development learning or memory insulin receptor signaling pathway organ morphogenesis positive regulation of macrophage chemotaxis neural crest cell development Schwann cell development positive regulation of telomere maintenance response to lipopolysaccharide regulation of stress-activated MAPK cascade intracellular signal transduction ERBB2-ERBB3 signaling pathway myelination positive regulation of cholesterol biosynthetic process insulin-like growth factor receptor signaling pathway regulation of cytoskeleton organization interleukin-34-mediated signaling pathway chemokine-mediated signaling pathway caveolin-mediated endocytosis regulation of Golgi inheritance positive regulation of macrophage proliferation positive regulation of neuroinflammatory response regulation of early endosome to late endosome transport autophagosome assembly negative regulation of T cell mediated immune response to tumor cell transcription, DNA-templated regulation of gene expression negative regulation of autophagy positive regulation of autophagy phosphorylation sensory perception of pain BMP signaling pathway positive regulation of cyclase activity cellular response to nutrient levels negative regulation of proteasomal ubiquitin-dependent protein catabolic process peptidyl-tyrosine autophosphorylation TORC1 signaling glucose homeostasis signal transduction in response to DNA damage positive regulation of transcription from RNA polymerase II promoter modulation of synaptic transmission protein stabilization negative regulation of T cell activation cartilage development positive regulation of ERK1 and ERK2 cascade interleukin-1-mediated signaling pathway cellular response to mechanical stimulus negative regulation of cholesterol efflux xenophagy negative regulation of TORC1 signaling positive regulation of xenophagy MAPK import into nucleus positive regulation of cell proliferation response to toxic substance positive regulation of cell migration response to estrogen positive regulation of translation positive regulation of transcription, DNA-templated cellular response to organic substance regulation of sequence-specific DNA binding transcription factor activity positive regulation of protein phosphorylation protein complex assembly DNA damage induced protein phosphorylation positive regulation of histone phosphorylation positive regulation of histone acetylation negative regulation of apolipoprotein binding arachidonic acid metabolic process gastrulation eye development brain development central nervous system projection neuron axonogenesis chordate embryonic development mitotic cell cycle terminal region determination terminal branching, open tracheal system R7 cell fate commitment imaginal disc-derived wing vein specification imaginal disc-derived wing morphogenesis leg disc proximal/distal pattern formation metamorphosis torso signaling pathway determination of adult lifespan fibroblast growth factor receptor signaling pathway cellular response to starvation negative regulation of macroautophagy lymph gland plasmatocyte differentiation lymph gland crystal cell differentiation tracheal pit formation in open tracheal system sevenless signaling pathway positive regulation of cell size positive regulation of photoreceptor cell differentiation dorsal appendage formation vascular endothelial growth factor receptor signaling pathway behavioral response to ethanol positive regulation of sequence-specific DNA binding transcription factor activity defense response to virus branching involved in open tracheal system development cellular response to arsenic-containing substance positive regulation of wound healing regulation of heart morphogenesis regulation of response to drug