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Invitrogen
SLC22A1 Monoclonal Antibody (2C5)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-15730
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2C5
Immunogen
Purified recombinant fragment of human SLC22A1 expressed in E. Coli.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
Concentration not determined
Storage buffer
ascites
Contains
0.03% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA5-15730 targets SLC22A1 in indirect ELISA, FACS and WB applications and shows reactivity with Human samples.
The MA5-15730 immunogen is purified recombinant fragment of human SLC22A1 expressed in E. Coli.
MA5-15730 detects SLC22A1 which has a predicted molecular weight of approximately 61.2kDa.
Target Information
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 1-Oct; DKFZp313N1010; FLJ25043; FLJ37489; H oct1_cds; organic cation transporter 1; solute carrier family 22 (organic cation transporter), member 1; SYK; unnamed protein product
Gene Aliases: HOCT1; OCT1; oct1_cds
UniProt ID: (Human) O15245
Entrez Gene ID: (Human) 6580
acetylcholine transmembrane transporter activity
neurotransmitter transporter activity
dopamine:sodium symporter activity
norepinephrine:sodium symporter activity
protein binding
monoamine transmembrane transporter activity
prostaglandin transmembrane transporter activity
pyrimidine nucleoside transmembrane transporter activity
choline transmembrane transporter activity
thiamine transmembrane transporter activity
putrescine transmembrane transporter activity
spermidine transmembrane transporter activity
quaternary ammonium group transmembrane transporter activity
transmembrane transporter activity
identical protein binding
xenobiotic transporter activity
(R)-carnitine transmembrane transporter activity
xenobiotic metabolic process
neurotransmitter transport
establishment or maintenance of transmembrane electrochemical gradient
quaternary ammonium group transport
prostaglandin transport
amine transport
putrescine transport
spermidine transport
organic hydroxy compound transport
acetylcholine transport
choline transport
thiamine transport
xenobiotic transport
protein homooligomerization
serotonin uptake
norepinephrine uptake
epinephrine uptake
transmembrane transport
thiamine transmembrane transport
metanephric proximal tubule development
purine-containing compound transmembrane transport
dopamine uptake
transport across blood-brain barrier
(R)-carnitine transmembrane transport
acyl carnitine transmembrane transport
spermidine transmembrane transport
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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