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Invitrogen
TCP-1 beta Monoclonal Antibody (5B5F5)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-15901
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
5B5F5
Immunogen
Purified recombinant fragment of human CCT2 expressed in E. Coli.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites
Contains
0.03% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA5-15901 targets CCT2 in indirect ELISA, WB applications and shows reactivity with Human samples.
The MA5-15901 immunogen is purified recombinant fragment of human CCT2 expressed in E. Coli. .
MA5-15901 detects CCT2 which has a predicted molecular weight of approximately 54kDa.
Target Information
TCP-1 beta is a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). The CCT complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the TCP-1 beta gene have been observed but not thoroughly characterized. A disease associated with TCP-1 beta protein dysfunction include epididymo-orchitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AI528772; c-cpn; CCT; CCT containing TCP-1-beta; CCT-beta; Cct1; CCT2; Ccta; chaperonin containing t-complex polypeptide 1, beta subunit; chaperonin containing t-complex polypeptide 1, subunit 2; chaperonin containing TCP1, subunit 2 (beta); chaperonin subunit 2 (beta); epididymis secretory sperm binding protein Li 100n; p63; T-complex protein 1, beta subunit; Tcp-1; TCP-1-beta; Tp63; TRic; unnamed protein product
Gene Aliases: 99D8.1; CCT-beta; CCTB; HEL-S-100n; PRO1633; TCP-1-beta
UniProt ID: (Human) P78371, (Rat) Q5XIM9, (Mouse) P80314
Entrez Gene ID: (Human) 10576, (Rat) 299809, (Mouse) 12461
protein folding
binding of sperm to zona pellucida
positive regulation of telomere maintenance via telomerase
protein stabilization
chaperone-mediated protein complex assembly
scaRNA localization to Cajal body
positive regulation of telomerase RNA localization to Cajal body
positive regulation of protein localization to Cajal body
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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