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Invitrogen
Somatostatin Monoclonal Antibody (YC7)
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FIGURE: 1 / 5
Somatostatin Antibody (MA5-16987) in IHC, ICC/IF
Life science alliance 2020 -
Figure S4. Specificity of pancreatic ductal adenocarcinoma-driven beta-cell depletion. (A, B, C, D) Formalin-fixed paraffin-embedded sections from control, pancreatitis (PPT), HFD-fed (HFD), or KC mice (n = 6) were immunostained with antibodies to insulin, glucagon, somatostatin, or PP and revealed by immunofluorescence. Representative pictures of normal or remnant islets are shown (left). INS+, GCG+, SST+,... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-16987
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Guinea pig,
Human,
Mouse,
Pig,
Rat
Published species
Human,
Mouse
Host/Isotype
Rat
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
YC7
Immunogen
Somatostatin conjugated to thyroglobulin.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
tissue culture supernatant
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: growth hormone release-inhibiting factor; prepro-somatostatin; preprosomatostatin; prosomatostatin; somatostatin 28; somatostatin precursor; somatostatin-14; somatostatin-28; somatotropin release-inhibiting factor; unnamed protein product
Gene Aliases: SMST; SOM; SRIF; SS; SS-14; SS-28; SST1
UniProt ID: (Human) P61278, (Pig) P01168, (Mouse) P60041, (Rat) P60042
Entrez Gene ID: (Human) 6750, (Pig) 494469, (Mouse) 20604, (Guinea pig) 100730851, (Rat) 24797
hyperosmotic response
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
cell-cell signaling
chemical synaptic transmission
response to nutrient
digestion
negative regulation of cell proliferation
hormone-mediated apoptotic signaling pathway
response to xenobiotic stimulus
response to acidic pH
regulation of cell migration
somatostatin signaling pathway
response to amino acid
response to steroid hormone
regulation of postsynaptic membrane neurotransmitter receptor levels
signal transduction
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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