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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-17130
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Non-human primate
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2C12
Immunogen
Purified recombinant fragment of human MSN expressed in E. Coli.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA5-17130 targets MSN in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with Human and Non-human primate samples.
The MA5-17130 immunogen is purified recombinant fragment of human MSN expressed in E. Coli.
MA5-17130 detects MSN which has a predicted molecular weight of approximately 67.8kDa.
Target Information
Moesin, a member of the talin-4. 1 superfamily, is a linking protein of the submembraneous actin cytoskeleton. It is expressed in macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. It is involved in cell adhesion, migration, and organization of cell surface structures.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: epididymis luminal protein 70; membrane-organizing extension spike protein; unnamed protein product
Gene Aliases: HEL70; IMD50
UniProt ID: (Human) P26038
Entrez Gene ID: (Human) 4478
immunological synapse formation
cytoskeleton organization
leukocyte cell-cell adhesion
regulation of cell shape
regulation of cell size
positive regulation of gene expression
gland morphogenesis
membrane to membrane docking
T cell proliferation
establishment of epithelial cell apical/basal polarity
positive regulation of protein catabolic process
leukocyte migration
establishment of endothelial barrier
T cell aggregation
T cell migration
regulation of organelle assembly
positive regulation of protein localization to early endosome
regulation of lymphocyte migration
positive regulation of early endosome to late endosome transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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