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Invitrogen
HOXA1/HOXB1/HOXD1 Monoclonal Antibody (2E5)
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Product Details
MA5-19111
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
2E5
Immunogen
HOXB1 (NP_002135.2, 101 a.a. ~ 210 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide Sequence: LGQSEGDGGY FHPSSYGAQL GGLSDGYGAG GAGPGPYPPQ HPPYGNEQTA SFAPAYADLL SEDKETPCPS EPNTPTARTF DWMKVKRNPP KTAKVSEPGL GSPSGLRTNF
Target Information
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 14 kDa polypeptide encoded by the shortest HOXA1 mRNA; 24 kDa polypeptide encoded by the longest HOXA1 transcript; 36 kDa homeodomain-containing protein encoded by the middle size HOXA1 transcript; homeo box 4G; homeo box A1; homeo box D1; homeobox 1F; Homeobox protein Hox-1F; Homeobox protein Hox-2I; Homeobox protein Hox-A1; Homeobox protein Hox-B1; Homeobox protein Hox-D1; Homeobox protein Hox-GG; Hox 1.6-like protein; HOX A1 homeodomain protein; HOXA1; lab-like protein; MGC45232; unnamed protein product
Gene Aliases: BSAS; HCFP3; Hox-2.9; Hox-4.7; HOX1; HOX1F; HOX2; HOX2I; HOX4; HOX4G; HOXA1; HOXB1; HOXD1
UniProt ID: (Human) P49639, (Human) P14653, (Human) Q9GZZ0
Entrez Gene ID: (Human) 3198, (Human) 3211, (Human) 3231
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
identical protein binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
protein domain specific binding
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
pattern specification process
anatomical structure morphogenesis
anterior/posterior pattern specification
rhombomere development
rhombomere 4 development
rhombomere 5 development
facial nerve structural organization
facial nucleus development
positive regulation of transcription from RNA polymerase II promoter
anatomical structure formation involved in morphogenesis
embryonic skeletal system morphogenesis
sensory perception of pain
neuron differentiation
embryonic skeletal system development
sensory perception of sound
optokinetic behavior
abducens nerve formation
outer ear morphogenesis
embryonic neurocranium morphogenesis
inner ear development
artery morphogenesis
regulation of behavior
cognition
neuromuscular process
artery development
semicircular canal formation
cochlea development
cochlea morphogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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