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Invitrogen
Plexin A2 Monoclonal Antibody (583603)
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FIGURE: 1 / 3
Plexin A2 Antibody (MA5-24263) in ICC/IF
Immunocytochemistry analysis of Plexin A2 in immersion fixed HUVEC human umbilical vein endothelial cells. Samples were incubated in Plexin A2 monoclonal antibody (Product # MA5-24263) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Rat IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to cell surfac... View More
Product Details
MA5-24263
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rat
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
583603
Immunogen
CHO-derived recombinant mouse Plexin A2 Met35-Pro1237
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
In direct ELISAs, no cross-reactivity with recombinant human Plexin A4, B1, B2, D1, recombinant mouse Plexin A1, A3, B3, or C1 is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Plexins are a family of large, transmembrane receptors for multiple classes of semaphorins in vertebrates. Plexins are widely expressed, and regions of their extracellular domain are homologus to both scatter factor receptors and semaphorin domains. Plexins may act as semaphorin receptors alone or in combination with neuropilins. Plexins are divided into four subfamilies designated plexin-A, -B, -C, and -D. Drosophila plexin-A is a receptor for class I semaphorins and controls motor and axon guidance. Plexin-A3 mediates cell-repelling cues. Plexins B and C are receptors for Sema 4 and Sema 7, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FLJ11751; FLJ30634; Plex 2; plexin 2; plexin-2; Plexin-A2; Semaphorin receptor OCT; transmembrane protein OCT; unnamed protein product
Gene Aliases: 2810428A13Rik; AA589422; AW457381; KIAA0463; mKIAA0463; OCT; PlexA2; PLXN2; PLXNA2; UNQ209/PRO235
UniProt ID: (Human) O75051, (Mouse) P70207
Entrez Gene ID: (Human) 5362, (Mouse) 18845
somitogenesis
cell surface receptor signaling pathway
nervous system development
synapse assembly
anatomical structure morphogenesis
neural tube development
cerebellar granule cell precursor tangential migration
regulation of cell migration
tube development
animal organ development
centrosome localization
pharyngeal system development
limb bud formation
semaphorin-plexin signaling pathway
signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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