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Invitrogen
PSMA2 Monoclonal Antibody (OTI3D9)
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FIGURE: 1 / 4
PSMA2 Antibody (MA5-26149) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded carcinoma of human liver tissue. To expose target proteins, 1 mM EDTA in 10mM Tris, pH6.0, 120°C for 3min was used. Following antigen retrieval, tissues were probed with a PSMA2 monoclonal antibody (Product # MA5-26149).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-26149
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Non-human primate,
Dog,
Human,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
OTI3D9
Immunogen
Human recombinant protein fragment corresponding to amino acids 50-234 of PSMA2 produced in E.coli
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha-2; macropain subunit C3; multicatalytic endopeptidase complex subunit C3; OTTHUMP00000207364; OTTHUMP00000207366; proteasome (prosome, macropain) subunit, alpha type 2; proteasome (prosome, macropain) subunit, alpha type, 2; proteasome alpha 2 subunit; proteasome component C3; proteasome component C3 protein; proteasome subunit alpha 2; proteasome subunit HC3; PSMA 2; PSMA2; unnamed protein product
Gene Aliases: HC3; Lmpc3; MU; PMSA2; PSC2
UniProt ID: (Human) P25787, (Mouse) P49722, (Rat) P17220
Entrez Gene ID: (Dog) 475870, (Human) 5683, (Mouse) 19166, (Rat) 29669
immune system process
DNA repair
ubiquitin-dependent protein catabolic process
apoptotic process
cellular response to DNA damage stimulus
response to oxidative stress
spermatogenesis
response to virus
proteasomal protein catabolic process
proteasomal ubiquitin-independent protein catabolic process
protein catabolic process
sperm motility
positive regulation of interferon-gamma production
positive regulation of interleukin-2 production
positive regulation of tumor necrosis factor production
response to interferon-gamma
proteasome-mediated ubiquitin-dependent protein catabolic process
CD8-positive, alpha-beta T cell differentiation
thymic T cell selection
T-helper 1 cell differentiation
negative regulation of regulatory T cell differentiation
meiotic cell cycle
regulation of proteasomal protein catabolic process
cellular response to type I interferon
T-helper 17 cell differentiation
CD8-positive, alpha-beta T cell homeostasis
regulation of G1/S transition of mitotic cell cycle
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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