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Invitrogen
Synaptotagmin 4 Monoclonal Antibody (OTI2F2)
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Product Details
MA5-26214
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
OTI2F2
Immunogen
Full length human recombinant protein of SYt4 produced in HEK293T cell
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
May be involved in Ca2+-dependent exocytosis of secretory vesicles through Ca2+ and phospholipid binding to the C2 domain or may serve as Ca2+ sensors in the process of vesicular trafficking and exocytosis. Plays a role in dendrite formation by melanocytes (PubMed:23999003).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Synaptotagmin IV; Synaptotagmin-4; Synaptotagmin4; SytIV; unnamed protein product
Gene Aliases: HsT1192; KIAA1342; SYT4
UniProt ID: (Human) Q9H2B2
Entrez Gene ID: (Human) 6860
vesicle fusion
neurotransmitter secretion
memory
positive regulation of glutamate secretion
regulation of dopamine secretion
vesicle-mediated transport
regulation of calcium ion-dependent exocytosis
regulation of endocytosis
cell differentiation
regulation of vesicle fusion
negative regulation of catecholamine secretion
negative regulation of calcium ion-dependent exocytosis
positive regulation of calcium ion-dependent exocytosis
negative regulation of short-term neuronal synaptic plasticity
negative regulation of protein secretion
calcium-dependent activation of synaptic vesicle fusion
dense core granule cytoskeletal transport
regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission
regulation of postsynaptic dense core vesicle exocytosis
negative regulation of secretion by cell
positive regulation of dendrite extension
positive regulation of dense core granule exocytosis
negative regulation of retrograde trans-synaptic signaling by neuropeptide
negative regulation of synaptic vesicle exocytosis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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