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Invitrogen
DLL1 Recombinant Rabbit Monoclonal Antibody (006)
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Product Details
MA5-31290
Product Specifications
Species Reactivity
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
006
Immunogen
Recombinant Rat DLL1 protein (Met1-Ser534)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Rat DLL1.
Target Information
Delta-like protein 1 (DLL1) is a transmembrane protein characterized by epidermal growth factor (EGF)-like repeats. It is a ligand for Notch receptor. It blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: delta1; drosophila Delta homolog 1; DSL ligand; OTTHUMP00000017690
UniProt ID: (Rat) P97677
Entrez Gene ID: (Rat) 84010
cell fate determination
somitogenesis
somite specification
heart looping
marginal zone B cell differentiation
type B pancreatic cell development
cell communication
Notch signaling pathway
cell-cell signaling
determination of left/right symmetry
compartment pattern specification
nervous system development
regulation of blood pressure
positive regulation of cell proliferation
negative regulation of cell proliferation
auditory receptor cell fate commitment
proximal/distal pattern formation
positive regulation of gene expression
astrocyte development
regulation of somitogenesis
spinal cord development
cerebellar molecular layer formation
cerebellar Purkinje cell layer structural organization
regulation of cell adhesion
negative regulation of epithelial cell differentiation
regulation of vascular endothelial growth factor receptor signaling pathway
negative regulation of interleukin-10 production
negative regulation of glial cell apoptotic process
organ growth
regulation of growth
cell fate commitment
negative regulation of cell differentiation
negative regulation of epidermal cell differentiation
negative regulation of auditory receptor cell differentiation
negative regulation of myeloid cell differentiation
negative regulation of myoblast differentiation
negative regulation of neuron differentiation
negative regulation of Notch signaling pathway
positive regulation of Notch signaling pathway
positive regulation of endocytosis
positive regulation of transcription from RNA polymerase II promoter
lateral inhibition
skeletal muscle tissue growth
regulation of skeletal muscle tissue growth
positive regulation of skeletal muscle tissue growth
neuron fate specification
inner ear development
regulation of neurogenesis
regulation of cell division
retina development in camera-type eye
retina morphogenesis in camera-type eye
Notch signaling pathway involved in arterial endothelial cell fate commitment
left/right axis specification
nephron development
proximal tubule development
loop of Henle development
clathrin-mediated endocytosis
energy homeostasis
endothelial tip cell fate specification
neuronal stem cell population maintenance
skin epidermis development
regulation of vascular endothelial growth factor signaling pathway
positive regulation of sprouting angiogenesis
negative regulation of cardiac muscle cell differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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