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Invitrogen
Synapsin 1 Monoclonal Antibody (7H10G6)
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FIGURE: 1 / 12
Synapsin 1 Antibody (MA5-31919) in ICC/IF
Immunocytochemistry analysis of Synapsin 1 in HepG2 cells (green). Sample was incubated with Synapsin 1 monoclonal antibody (Product # MA5-31919) using a dilution of 1:200-1:1000 followed by DRAQ5 fluorescent DNA dye (blue), and Alexa Fluor- 555 phalloidin (red labeled actin filaments) .
Product Details
MA5-31919
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Published species
Bacteria,
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
7H10G6
Immunogen
Purified recombinant fragment of human SYN1 (AA: 362-511) expressed in E. coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA5-31919 has been tested in indirect ELISA.
Target Information
SYN1 (synapsin 1) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins that associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains and are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. Synapsin 1 plays a role in regulation of axonogenesis and synaptogenesis. It serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Brain protein 4.1; synapsin 1; Synapsin I; synapsin Ib; Synapsin-1; truncated synapsin 1-S
Gene Aliases: EPILX; EPILX1; MRX50; Syn-1; SYN1; Syn1-S; SYN1a; SYN1b; SYNI
UniProt ID: (Human) P17600, (Rat) P09951, (Mouse) O88935
Entrez Gene ID: (Human) 6853, (Rat) 24949, (Mouse) 20964
chemical synaptic transmission
neurotransmitter secretion
regulation of neurotransmitter secretion
neuron development
modulation of synaptic transmission
synapse organization
synaptic vesicle clustering
regulation of synaptic vesicle cycle
synaptic vesicle cycle
regulation of synaptic vesicle exocytosis
metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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