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Invitrogen
HuR Recombinant Rabbit Monoclonal Antibody (JM96-33)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-32777
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JM96-33
Immunogen
Synthetic peptide within Human HuR ELAVL1 aa 50-99.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It destabilizes mRNAs and thereby regulates gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R); ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); ELAV like 1; elav-like generic protein; embryonic lethal, abnormal vision, drosophila, homolog-like 1; Hu antigen R; HU-antigen A; hu-antigen R; Human antigen R; melG; mRNA-stabilizing factor HuR; unnamed protein product
Gene Aliases: 2410055N02Rik; ELAV1; Hua; HUR; MelG
UniProt ID: (Human) Q15717, (Rat) B5DF91, (Mouse) P70372
Entrez Gene ID: (Human) 1994, (Rat) 363854, (Mouse) 15568
lncRNA-mediated post-transcriptional gene silencing
protein import into nucleus
cell proliferation
response to glucose
positive regulation of autophagy
posttranscriptional gene silencing
positive regulation of superoxide anion generation
regulation of mRNA stability
positive regulation of translation
positive regulation of autophagosome size
mRNA stabilization
protein homooligomerization
negative regulation of gene silencing by miRNA
mRNA destabilization
3'-UTR-mediated mRNA stabilization
regulation of stem cell population maintenance
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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