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Invitrogen
Syntrophin alpha-1 Recombinant Rabbit Monoclonal Antibody (JG35-62)
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FIGURE: 1 / 9
Syntrophin alpha-1 Antibody (MA5-34733) in ICC/IF
Immunofluorescent analysis of Syntrophin alpha 1 in HepG2 cells (green). Samples were fixed in paraformaldehyde and permeabilised with 0.25% Triton X100/PBS, incubated with Syntrophin alpha 1 monoclonal antibody (Product # MA5-34733), followed by DAPI (blue).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-34733
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JG35-62
Immunogen
Synthetic peptide within Human Syntrophin alpha 1 aa 1-49.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: HepG2, LOVO, SiHa, human colon tissue, human skeletal muscle tissue, mouse colon tissue, mouse skeletal muscle tissue.
Target Information
Syntrophin alpha-1 (Dystrophin, SNTA1) is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 59 kDa dystrophin-associated protein A1 acidic component 1; acidic alpha 1 syntrophin; dystrophin-associated protein A1, 59kDa, acidic component; pro-TGF-alpha cytoplasmic domain-interacting protein 1; RP23-192L3.1; syntrophin-1; unnamed protein product
Gene Aliases: dJ1187J4.5; LQT12; SNT1; TACIP1
UniProt ID: (Human) Q13424
Entrez Gene ID: (Human) 6640
regulation of heart rate
muscle contraction
positive regulation of Rac protein signal transduction
camera-type eye development
regulation of ventricular cardiac muscle cell membrane repolarization
ventricular cardiac muscle cell action potential
synaptic signaling
regulation of sodium ion transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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