Search
Invitrogen
CES1 Recombinant Rabbit Monoclonal Antibody (7C9R6)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-35117
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
7C9R6
Immunogen
Synthetic peptide
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.8 mg/mL
Amount
80 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MWLRAFILAT LSASAAWGHP SSPPVVDTVH GKVLGKFVSL EGFAQPVAIF LGIPFAKPPL GPLRFTPPQP AEPWSFVKNA TSYPPMCTQD PKAGQLLSEL
Target Information
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: acyl coenzyme A:cholesterol acyltransferase; acyl-coenzyme A:cholesterol acyltransferase; brain carboxylesterase hBr1; carboxyesterase ES-1; carboxyesterase ES-3; carboxylesterase 1; carboxylesterase 1 (monocyte/macrophage serine esterase 1); carboxylesterase 2 (liver); carboxylesterase precursor (EC 3.1.1.1); carboxylesterase; ACAT; cholesteryl ester hydrolase; cocaine carboxylesterase; E1; egasyn; endoplasmic reticulum-targeting protein of beta-glucuronidase; ER-resident carboxylesterase; ES-HTEL; ES-THET; ES-x; esterase 1; Esterase 2 member of carboxylesterase-cluster 1; esterase 2, member of carboxylesterase-cluster 1; esterase 22; esterase-2; esterase-22; human monocyte/macrophage serine esterase 1; liver carboxylesterase 1; liver carboxylesterase 22; liver carboxylesterase 3; liver carboxylesterase N; lung surfactant convertase; methylumbelliferyl-acetate deacetylase 1; MGC117365; microsomal carboxyesterase E1-like; monocyte/macrophage serine esterase; neutral retinyl ester hydrolase; NREH; PES-N; pI 5.5 esterase; REH; retinyl ester hydrolase; serine esterase 1; triacylglycero; triacylglycerol hydrolase; unnamed protein product
Gene Aliases: ACAT; CE-1; CEH; Ces-1; Ces-N; Ces1; Ces1l; CES2; Ee-1; Ee1; Eg; EG244595; egasyn; Es-22; Es-4; Es-N; Es1; Es2; Es22; Es4; EsN; Gm4976; hCE-1; HMSE; HMSE1; PCE-1; PESN; REH; Ses-1; SES1; TGH
UniProt ID: (Human) P23141, (Mouse) P23953, (Rat) P10959, (Mouse) Q64176, (Mouse) Q8VCC2
Entrez Gene ID: (Human) 1066, (Mouse) 244595, (Rat) 679817, (Mouse) 13884, (Rat) 24346, (Rat) 29225, (Mouse) 13897, (Mouse) 12623
sterol esterase activity
protein binding
methylumbelliferyl-acetate deacetylase activity
retinyl-palmitate esterase activity
carboxylesterase activity
carboxylic ester hydrolase activity
hydrolase activity, acting on ester bonds
protein homodimerization activity
all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity
fatty-acyl-ethyl-ester synthase activity
cholesterol metabolic process
response to bacterium
regulation of gene expression
positive regulation of cholesterol efflux
negative regulation of cholesterol storage
short-chain fatty acid catabolic process
chylomicron assembly
retinol metabolic process
reverse cholesterol transport
regulation of bile acid biosynthetic process
positive regulation of cholesterol metabolic process
regulation of triglyceride metabolic process
regulation of chylomicron remnant clearance
regulation of bile acid secretion
retinoid metabolic process
cholesterol biosynthetic process
response to toxic substance
epithelial cell differentiation
cholesterol homeostasis
medium-chain fatty acid metabolic process
cellular response to cholesterol
cellular response to low-density lipoprotein particle stimulus
cholesterol ester hydrolysis involved in cholesterol transport
vitamin A biosynthetic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support