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Invitrogen
PGAM1 Recombinant Rabbit Monoclonal Antibody (7V9H9)
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FIGURE: 1 / 2
PGAM1 Antibody (MA5-35455) in IHC (P)
Immunohistochemistry analysis of PGAM1 in paraffin-embedded human appendix. Samples were incubated with PGAM1 Monoclonal antibody (Product # MA5-35455) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-35455
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
7V9H9
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PGAM1 (P18669)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.83 mg/mL
Amount
83 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MAAYKLVLIR HGESAWNLEN RFSGWYDADL SPAGHEEAKR GGQALRDAGY EFDICFTSVQ KRAIRTLWTV LDAIDQMWLP VVRTWRLNER HYGGLTGLNK
Target Information
PGAM1 belongs to the phosphoglycerate mutase family. PGAM1 is an important component of glucose and 2,3-BPGA (2,3-bisphosphoglycerate) metabolism and catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The PGAM1 protein is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). Mutations in PGAM1 cause muscle phosphoglycerate mutase efficiency, also known as glycogen storage disease X. Recombinant human PGAM protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BPG-dependent PGAM 1; epididymis secretory protein Li 35; PGAM-B; PGAM1; phosphoglycerate mutase 1 (brain); phosphoglycerate mutase A, nonmuscle form; phosphoglycerate mutase isozyme B; RP11-452K12.8; similar to Homo sapiens phosphoglycerate mutase (PGAM-B) mRNA with GenBank Accession Number J04173.1; unnamed protein product
Gene Aliases: 2310050F24Rik; HEL-S-35; Pgam-1; PGAM-B; PGAMA; Pgmut
UniProt ID: (Human) P18669, (Mouse) Q9DBJ1, (Rat) P25113
Entrez Gene ID: (Human) 5223, (Mouse) 18648, (Rat) 24642
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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