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Invitrogen
MCAK Recombinant Rabbit Monoclonal Antibody (7V9D2)
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FIGURE: 1 / 1
MCAK Antibody (MA5-35762) in WB
Western blot analysis of MCAK in extracts of various cell lines. Samples were incubated with MCAK Monoclonal antibody (Product # MA5-35762) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3 min.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-35762
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
7V9D2
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human KIF2C/KIF2C/MCAK (Q99661)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.29 mg/mL
Amount
129 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MAMDSSLQAR LFPGLAIKIQ RSNGLIHSAN VRTVNLEKSC VSVEWAEGGA TKGKEIDFDD VAAINPELLQ LLPLHPKDNL PLQENVTIQK QKRRSVNSKI
Target Information
The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HsMCAK; KIF2C; kinesin-like protein 6; mitotic centromere-associated kinesin; RP11-269F19.1; testis tissue sperm-binding protein Li 68n; TS-MSAK; unnamed protein product
Gene Aliases: CT139; KNSL6; MCAK
UniProt ID: (Human) Q99661
Entrez Gene ID: (Human) 11004
mitotic sister chromatid segregation
microtubule-based movement
microtubule depolymerization
mitotic metaphase plate congression
establishment or maintenance of microtubule cytoskeleton polarity
metaphase plate congression
attachment of mitotic spindle microtubules to kinetochore
regulation of chromosome segregation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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