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Invitrogen
Dabigatran (Idarucizumab Biosimilar) Recombinant Humanized mouse Monoclonal Antibody
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FIGURE: 1 / 1
Dabigatran (Idarucizumab Biosimilar) Antibody (MA5-41998) in SDS-PAGE
SDS-PAGE analysis of the recombinant Pradaxa (Dabigatran Etexilate Mesylate) dabigatran etexilate mesylate protein expressed in CHO cells using a Dabigatran (Idarucizumab Biosimilar) monoclonal antibody (Product # MA5-41998). R denotes the lane was run under reducing conditions. NR denotes the lane was run under non-reducing conditions.
Product Details
MA5-41998
Product Specifications
Species Reactivity
Chemical
Host/Isotype
Artificial Control
/ IgG1, F(ab), kappa
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Immunogen
Pradaxa (Dabigatran Etexilate Mesylate) dabigatran etexilate mesylate
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2.53 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
30mM histidine/PBS, pH 6.0, with 10% sucrose, 60ppm Tween 80
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
Target Information
Dabigatran is an oral direct thrombin (factor IIa) inhibitor used as an anticoagulant. It works by selectively and reversibly blocking thrombin, preventing the conversion of fibrinogen to fibrin and thereby reducing blood clot formation. Dabigatran is commonly prescribed for stroke prevention in patients with nonvalvular atrial fibrillation and for the treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE). It is administered as the prodrug dabigatran etexilate and does not require routine coagulation monitoring. An approved reversal agent (idarucizumab) is available for emergency situations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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