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Invitrogen
FGF10 Monoclonal Antibody (04)
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Product Details
MA5-42993
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
04
Immunogen
Recombinant Human FGF10/KGF2 protein (38-208).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Specificity: Human FGF10/KGF2
Target Information
FGF10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This protein is also implicated to be a primary factor in the process of wound healing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FGF; FGF-10; FGF10; Fibroblast growth factor; fibroblast growth factor 10; FGF10; keratinocyte growth factor 2; keratinocyte growth factor-2; KGF2; produced by fibroblasts of urinary bladder lamina propria
Gene Aliases: LADD3
UniProt ID: (Human) O15520
Entrez Gene ID: (Human) 2255
angiogenesis
metanephros development
mesonephros development
salivary gland development
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
positive regulation of epithelial cell migration
positive regulation of keratinocyte proliferation
neurogenesis
actin cytoskeleton organization
cell differentiation
regulation of cell migration
response to estradiol
response to lipopolysaccharide
positive regulation of ATPase activity
lacrimal gland development
protein localization to cell surface
wound healing
tissue regeneration
positive regulation of MAPK cascade
positive regulation of DNA repair
positive regulation of transcription, DNA-templated
positive regulation of Ras protein signal transduction
regulation of saliva secretion
thymus development
branching morphogenesis of an epithelial tube
positive regulation of lymphocyte proliferation
epithelial cell proliferation
urothelial cell proliferation
positive regulation of urothelial cell proliferation
positive regulation of epithelial cell proliferation
positive regulation of peptidyl-tyrosine phosphorylation
positive chemotaxis
positive regulation of keratinocyte migration
radial glial cell differentiation
positive regulation of epithelial cell proliferation involved in wound healing
lung epithelium development
lung saccule development
bud outgrowth involved in lung branching
secretion by lung epithelial cell involved in lung growth
tear secretion
ERK1 and ERK2 cascade
positive regulation of hair follicle cell proliferation
positive regulation of G1/S transition of mitotic cell cycle
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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