Search
Invitrogen
14-3-3 eta Monoclonal Antibody (3G12)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 2
14-3-3 eta Antibody (MA5-47318) in ICC/IF
Immunofluorescent analysis of 14-3-3 eta in HeLa cells. Samples were stained with 14-3-3 eta monoclonal antibody (Product # MA5-47416) using a dilution of 1:1,000 (red). Blue is DAPI staining of nuclear DNA. The 14-3-3 eta antibody reveals the diffuse cytoplasmic distribution of 14-3-3 eta protein with higher concentration in the perinuclear region.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-47318
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Dog,
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3G12
Immunogen
Full length human recombinant 14-3-3 (eta) protein expressed in and purified from E.coli.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
500 µg
Purification
Protein G
Storage buffer
PBS with 50% glycerol
Contains
5mM sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 14-3-3 eta; 14-3-3 protein eta chain; 14-3-3 protein eta-subtype; 14-3-3n; 1433F; AS1; brain-specific tyrosine and tryptophan hydroxylase activator; KCIP-1; protein kinase C inhibitor protein 1; similar to Homo sapiens DNA for 14-3-3 protein eta chain, exon 2 with GenBank Accession Number D78577.1; tyrosine 3-monooxygenase/tryotophan 5-monooxygenase activation protein; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide; unnamed protein product; YWHA114-3-3 eta; YWHAH
Gene Aliases: 14-3-3e; YWHA1
UniProt ID: (Human) Q04917, (Bovine) P68509, (Mouse) P68510, (Rat) P68511
Entrez Gene ID: (Dog) 100687866, (Human) 7533, (Bovine) 282126, (Mouse) 22629, (Rat) 25576
regulation of sodium ion transport
glucocorticoid catabolic process
intracellular protein transport
signal transduction
protein localization
substantia nigra development
glucocorticoid receptor signaling pathway
regulation of neuron differentiation
positive regulation of transcription, DNA-templated
regulation of synaptic plasticity
negative regulation of dendrite morphogenesis
membrane depolarization during action potential
presynaptic modulation of chemical synaptic transmission
regulation of sodium ion transmembrane transporter activity
cytoskeleton organization
regulation of mitotic nuclear division
negative regulation of apoptotic process
establishment of protein localization
biological_process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support