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Invitrogen
Hepatitis B Virus Core/Ayw/Adw Monoclonal Antibody (1822)
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Product Details
MA5-47486
Product Specifications
Species Reactivity
Virus
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
1822
Immunogen
Proprietary sequence
Conjugate
Form
Liquid
Concentration
100 µg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.2
Contains
0.1% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Specificity: Reactive with adw, ayw, and Hb core antigens. Negative to normal human serum.
Best ELISA pairs (capture/conjugate): Hepatitis B Virus Core/Ayw/Adw Monoclonal antibody (Product # MA5-47486)/Hepatitis B Virus Core/Ayw/Adw Monoclonal antibody (Product # MA5-47487); Hepatitis B Virus Core/Ayw/Adw Monoclonal antibody (Product # MA5-47486)/Hepatitis B Virus Core/Ayw/Adw Monoclonal antibody (Product # MA5-47486); Hepatitis B Virus Core/Ayw/Adw Monoclonal antibody (Product # MA5-47486)/Hepatitis B Virus Core/Ayw/Adw Monoclonal antibody (Product # MA5-47488).
Purified preparations consist of >90% pure mouse monoclonal antibody which has been purified from ascites fluid by protein A chromatography. The final preparation is formulated to a protein concentration of 100 µg/mL in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1% sodium azide. Each vial contains 1.0 mL. This product contains no stabilizing proteins and should be stored at 4C until ready for use. Working dilution must be determined by the user. Suggested starting ranges are 1:10-1:50 for ICC/IF and 1:20-1:200. for ELISA.
Target Information
The hepatitis B virus is an important cause of acute and chronic liver disease. It is also the most common form of parenterally transmitted viral hepatitis. Hepatitis B virus is spherical in shape with a diameter of 42nm. It contains a 27 nm partially double stranded DNA core enclosed within a lipoprotein coat. The antigenic activity of the nucleocapsid core is designated as hepatitis B core antigen. The antigens in the outer surface are called as hepatitis B virus surface antigens. Core antigens are localized within the nuclei whereas the surface antigens are present in the cytoplasm of the infected cells. Antibodies to surface antigens appear in circulation at an early stage of infection whereas the antibodies to the core antigens are detected after several weeks. The virus is estimated to affect some 350 million people worldwide. Immunization against hepatitis B is an important component of preventative medicine and is offered to all children in approximately 30 countries. Hepatitis B virus (HBV) belongs to the Hepadnaviridae family and infection with HBV is usually more serious than infection with hepatitis A virus. In some individuals the infection is not cleared and followed by persistent intracellular viral carriage that can lead to the development of hepatocelular carcinomas. There are currently 400 million HBV carriers worldwide making HBV one of the most common human pathogens.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Hepatitis B suface antigen
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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