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Invitrogen
NAPSA Monoclonal Antibody (5A6E4)
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Product Details
MA5-48670
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
5A6E4
Immunogen
Synthesized peptide of human NAPSA (AA: KPIFVPLSNYRDVQYc).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Napsin 1 is an aspartic protease that is generally expressed in the lung, but also present in kidney and in metastatic carcinomas throughout the body. Napsin 1 processes surfactant protein B in healthy pulmonary and renal tissues, but is abnormally regulated when carcinogenesis occurs. Thus, many researchers have found napsin evaluation to be useful in identifying several cancers, and differentiating primary tumors from metastases. When combined with thyroid transcription factor analysis, napsin can be used as a specific biomarker for differentiation of carcinoma types. Napsin has also been associated with pulmonary alveolar proteinosis as well as in protein catabolism in renal tubules.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: asp 4; ASP4; aspartic proteinase; Aspartyl protease 4; kidney-derived aspartic protease-like protein; Napsin-1; Napsin-A; NR1H2 antisense RNA 1; pronapsin A; TA01/TA02
Gene Aliases: KAP; Kdap; NAP1; NAPA; NAPSA; NR1H2-AS1; SNAPA
UniProt ID: (Human) O96009
Entrez Gene ID: (Human) 9476
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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