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Invitrogen
POLE Recombinant Rabbit Monoclonal Antibody (HL2150)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-50403
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL2150
Immunogen
Recombinant fragment of human POLE.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2 mg/mL
Amount
200 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
POLE (Polepsi) is present in proliferating cells and is implicated in repair of UV-damaged DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3'-5' exodeoxyribonuclease; DNA polymerase epsilon catalytic subunit protein; DNA polymerase II subunit A; DNA-directed DNA polymerase epsilon; pol-epsilon; polymerase (DNA directed), epsilon, catalytic subunit; polymerase (DNA) epsilon, catalytic subunit; unnamed protein product
Gene Aliases: CRCS12; FILS; IMAGEI; POLE1
UniProt ID: (Human) Q07864, (Mouse) Q9WVF7
Entrez Gene ID: (Human) 5426, (Mouse) 18973
G1/S transition of mitotic cell cycle
DNA synthesis involved in DNA repair
DNA metabolic process
DNA replication
DNA-dependent DNA replication
leading strand elongation
DNA repair
base-excision repair, gap-filling
nucleotide-excision repair, DNA gap filling
DNA replication proofreading
embryonic organ development
DNA biosynthetic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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