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Invitrogen
DCLK1 Monoclonal Antibody (C9)
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FIGURE: 1 / 7
DCLK1 Antibody (MA5-50941) in IHC (P)
Immunohistochemistry (Paraffin) analysis of DCLK1 in rat cardiac muscle tissue using DCLK1 Monoclonal Antibody (C9) (Product # MA5-50941) (20 µg/mL) and using PBS intead of the primary antibody as a control. The sample was then stained with HRP-Goat anti-Mouse IgG polyclonal secondary antibody (2 µg/mL). DAB staining.
Product Details
MA5-50941
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Pig,
Rat
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
C9
Immunogen
Recombinant Human DCLK1 protein, Tyr390-Val647 (Accession #O15075)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
200 µg
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% Proclin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
DCAMKL1 (DCLK1) serine/threonine kinase or DCLK1 or doublecortin-like kinase 1 contains two N-terminal doublecortin domains (which bind microtubules and regulate microtubule polymerization), a C-terminal serine/threonine protein kinase domain (which shows substantial homology to Ca2+/calmodulin-dependent protein kinase), and a serine/proline-rich domain in between the doublecortin and the protein kinase domains (which mediates multiple protein-protein interactions). DCAMKL1 is a microtubule-associated kinase that can undergo autophosphorylation. DCAMKL1 has microtubule-polymerizing activity that is independent of its protein kinase activity. DCAMKL1 is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Calcium/calmodulin-dependent protein kinase type I-like CPG16; double cortin and calcium/calmodulin-dependent protein kinase-like 1; Doublecortin domain-containing protein 3A; Doublecortin-like and CAM kinase-like 1; Doublecortin-like kinase 1; KIAA0369; RP11-113P14.1; Serine/threonine-protein kinase DCLK1; unnamed protein product
Gene Aliases: Ania4; CL1; CLICK1; Cpg16; DCAMKL1; DCDC3A; DCLK; DCLK1; KIAA0369
UniProt ID: (Human) O15075, (Rat) O08875
Entrez Gene ID: (Human) 9201, (Pig) 100623824, (Rat) 83825
protein phosphorylation
nervous system development
central nervous system development
response to virus
endosomal transport
cell differentiation
protein localization to nucleus
intracellular signal transduction
axon extension
neuron migration
axonogenesis
brain development
central nervous system projection neuron axonogenesis
forebrain development
dendrite morphogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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