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Invitrogen
CK1 delta Monoclonal Antibody (C3)
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FIGURE: 1 / 5
CK1 delta Antibody (MA5-50957) in IHC (P)
Immunohistochemistry (Paraffin) analysis of CK1 delta in human cerebrum tissue using CK1 delta Monoclonal Antibody (C3) (Product # MA5-50957) (30 µg/mL) and using PBS intead of the primary antibody as a control. The sample was then stained with HRP-Goat anti-Mouse IgG polyclonal secondary antibody (2 µg/mL). DAB staining.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-50957
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Pig,
Rat
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
C3
Immunogen
Recombinant Human CSNK1d protein, Met1-Lys409 (Accession #P48730)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
200 µg
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% Proclin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
CSNK1D (CK1 delta), a serine/threonine kinase, plays a critical role in Wnt/beta-catenin signaling pathway. This pathway is important in both development and cancer. The encoded protein may also be involved in the regulation of apoptosis, circadian rhythm, microtubule dynamics, chromosome segregation, and p53-mediated effects on growth. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Three transcript variants encoding different isoforms have been found for CK1 delta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: casein kinase 1; casein kinase 1, delta tv1; casein kinase 1, delta tv2; casein kinase I; CK1d; CK1delta; HGNC:2452; tau-protein kinase CSNK1D; unnamed protein product
Gene Aliases: ASPS; CKI-delta; CKId; CKIdelta; FASPS2; HCKID
UniProt ID: (Human) P48730, (Rat) Q06486
Entrez Gene ID: (Human) 1453, (Pig) 100625051, (Rat) 64462
protein phosphorylation
endocytosis
microtubule nucleation
Golgi organization
signal transduction
regulation of Wnt signaling pathway
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
circadian regulation of gene expression
protein localization to Golgi apparatus
regulation of circadian rhythm
COPII vesicle coating
spindle assembly
protein localization to cilium
protein localization to centrosome
positive regulation of canonical Wnt signaling pathway
midbrain dopaminergic neuron differentiation
non-motile cilium assembly
positive regulation of non-canonical Wnt signaling pathway
positive regulation of Wnt signaling pathway
cellular response to nerve growth factor stimulus
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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